Per2 (NM_011066) Mouse Untagged Clone

CAT#: MC224087

Per2 (untagged) - Mouse period homolog 2 (Drosophila) (Per2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Per2
• Synonyms: mKIAA0347; mPer2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224087 representing NM_011066
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAATGGATACGTGGACTTCTCCCCAAGTCCCACCAGTCCCACCAAGGAGCCAGGGGCACCTCAGCCCA
  CCCAGGCTGTGCTCCAGGAAGACGTGGACATGAGCAGTGGCTCCAGCGGAAACGAGAACTGCTCCACGGG
  ACGGGACTCTCAGGGCAGTGACTGCGACGACAATGGGAAGGAGCTGCGGATGCTCGTGGAATCTTCCAAC
  ACTCACCCCAGCCCTGATGATGCCTTCAGACTCATGATGACAGAGGCAGAGCACAACCCCTCCACGAGCG
  GCTGCAGTAGTGAGCAGTCTGCCAAAGCTGACGCACACAAAGAACTGATAAGGACCCTGAAGGAGCTGAA
  GGTCCACCTCCCTGCAGACAAGAAGGCCAAGGGGAAGGCCAGCACGCTGGCAACCTTGAAGTATGCCCTG
  CGGAGCGTGAAGCAGGTGAAGGCTAATGAGGAGTACTACCAGCTGCTAATGTCCAGTGAGAGCCAGCCCT
  GCAGTGTGGATGTGCCTTCCTACAGCATGGAGCAGGTTGAGGGCATTACCTCCGAGTATATCGTGAAGAA
  CGCGGATATGTTTGCTGTGGCTGTGTCCCTGGTTTCTGGGAAGATCCTGTACATCTCTAACCAAGTGGCC
  TCCATCTTTCACTGTAAGAAGGACGCCTTCAGTGATGCCAAGTTTGTGGAGTTCCTGGCTCCTCATGACG
  TCAGTGTGTTCCACAGCTACACCACCCCTTACAAGCTTCCGCCCTGGAGTGTGTGCAGCGGCTTAGATTC
  TTTCACTCAGGAGTGCATGGAGGAGAAATCTTTTTTCTGCCGTGTCAGTGTTGGGAAACACCACGAGAAT
  GAGATTCGCTACCAGCCCTTCCGCATGACACCCTACCTGGTCAAGGTGCAAGAGCAGCAGGGTGCTGAGA
  GCCAGCTCTGCTGCCTGCTGCTGGCAGAGAGGGTACACTCGGGCTATGAAGCGCCTAGAATCCCTCCTGA
  GAAGAGGATCTTCACAACAACCCACACACCAAACTGCTTGTTCCAGGCTGTGGATGAAAGGGCGGTCCCC
  CTCCTGGGCTATCTACCTCAGGATCTGATCGAGACGCCTGTGCTCGTGCAGCTCCACCCCAGCGACCGGC
  CCTTGATGCTCGCCATCCACAAGAAGATCCTACAGGCCGGTGGACAGCCTTTCGATTATTCTCCCATTCG
  ATTCCGCACCCGCAACGGGGAGTACATCACACTGGACACTAGCTGGTCCAGCTTCATCAACCCGTGGAGC
  AGGAAGATATCTTTCATCATTGGGAGGCACAAAGTCAGGGTAGGCCCTTTGAATGAGGATGTGTTCGCAG
  CCTCCCCGTGCCCAGAGGAGAAGACTCCGCACCCCAGCGTTCAGGAGCTCACAGAACAAATCCACCGGCT
  ACTGATGCAGCCTGTCCCCCACAGCGGCTCCAGTGGCTATGGGAGCCTGGGCAGTAACGGATCCCACGAA
  CACCTCATGAGCCAGACATCATCCAGCGACAGCAATGGCCAAGAGGAGTCTCACCGGAGGAGATCCGGAA
  TTTTTAAAACCAGTGGCAAGATTCAAACCAAAAGTCACGTTTCTCATGAGTCTGGAGGACAGAAGGAAGC
  ATCTGTTGCAGAAATGCAAAGCAGCCCCCCAGCTCAGGTGAAAGCTGTCACCACCATAGAAAGGGACAGC
  TCAGGGGCCAGCCTACCCAAGGCCAGCTTCCCAGAGGAACTAGCCTATAAGAACCAGCCTCCTTGCTCCT
  ACCAGCAGATCAGCTGCCTGGACAGTGTCATCAGGTACCTGGAGAGCTGCAGCGAGGCAGCCACCCTGAA
  AAGGAAGTGCGAGTTCCCAGCCAACATCCCATCCCGGAAGGCCACAGTCAGCCCCGGGCTGCACTCTGGA
  GAGGCAGCGCGGCCCTCCAAGGTGACCAGCCACACAGAGGTCAGTGCTCACCTGAGCTCCCTGACGCTGC
  CAGGCAAGGCCGAGAGTGTGGTGTCCCTCACCAGCCAGTGCAGCTACAGCAGCACCATCGTGCATGTGGG
  CGACAAAAAGCCACAGCCCGAGCTAGAGACGGTAGAAGATATGGCCAGTGGGCCCGAGTCCCTGGATGGT
  GCGGCCGGCGGCCTCAGCCAAGAAAAGGGGCCTCTTCAGAAGTTGGGCCTCACCAAGGAAGTTCTGGCTG
  CACATACACAGAGAGAGGAGCAGGGCTTCCTGCAGAGGTTCAGGGAGGTGAGCAGGCTCAGTGCCCTGCA
  GGCTCACTGCCAGAACTATCTCCAGGAGCGGTCCCGAGCCCAGGCGAGTGATCGAGGACTAAGAAATACT
  TCTGGACTAGAGTCATCTTGGAAAAAAACTGGAAAGAACAGGAAACTGAAGTCAAAACGCGTCAAGACTC
  GGGACTCTTCTGAGAGCACAGGGTCTGGAGGACCAGTGTCCCACCGACCTCCCCTCATGGGCCTGAATGC
  CACAGCCTGGTCACCCTCCGACACATCCCAGTCCAGCTGCCCCTCTGCACCCTTCCCCACCGCAGTGCCA
  GCTTACCCCCTACCTGTGTTCCAGGCACCCGGAATAGTATCCACACCAGGGACGGTGGTGGCGCCACCTG
  CAGCCACCCACACTGGCTTCACCATGCCTGTTGTGCCTATGGGCACCCAGCCTGAATTCGCAGTGCAGCC
  CCTGCCATTCGCTGCCCCTTTGGCTCCTGTCATGGCCTTCATGCTGCCCAGCTACCCGTTCCCACCAGCA
  ACCCCAAACCTGCCTCAGGCCTTCCTCCCCAGCCAGCCTCACTTTCCAGCCCACCCCACACTTGCCTCCG
  AAATAACTCCTGCCTCCCAGGCTGAGTTCCCTAGTCGGACCTCGACGCTCAGACAGCCGTGCGCTTGCCC
  AGTCACCCCTCCAGCCGGCACAGTGGCCCTGGGCAGAGCCTCCCCACCGCTCTTCCAGTCCAGAGGCAGT
  AGTCCCCTACAACTTAACCTGCTTCAGCTAGAGGAGGCGCCTGAAGGCAGCACTGGAGCCGCAGGGACCC
  TGGGGACCACAGGGACAGCAGCTTCTGGTCTGGACTGCACATCTGGCACATCTCGGGATCGGCAGCCAAA
  GGCACCTCCAACATGCAACGAGCCCTCAGACACTCAGAACAGTGATGCCATCTCCACGTCAAGTGACCTG
  CTCAACCTCCTTCTGGGCGAGGACCTCTGCTCGGCCACTGGCTCAGCCCTGTCTAGAAGCGGGGCATCCG
  CCACCTCAGACTCTCTGGGCTCCAGCTCGCTGGGCTTCGGCACATCCCAAAGTGGGGCAGGCAGTAGTGA
  CACAAGTCACACCAGCAAATACTTTGGAAGCATTGACTCTTCAGAGAATAATCACAAAGCAAAAATGATC
  CCAGACACGGAGGAAAGCGAGCAGTTCATTAAGTACGTCTTGCAGGACCCCATCTGGCTGCTGATGGCCA
  ACACAGACGACAGCATCATGATGACATACCAGCTGCCCTCCCGGGATCTCCAGGCGGTGTTGAAGGAGGA
  CCAGGAGAAGCTGAAGCTGCTGCAGAGGTCCCAGCCCCGGTTCACAGAGGGCCAGAGGCGAGAGCTCCGA
  GAGGTTCATCCGTGGGTCCACACTGGGGGCCTGCCTACGGCCATCGATGTGACAGGCTGTGTTTACTGCG
  AGAGTGAGGAGAAAGGCAACATTTGCCTGCCATATGAGGAAGACAGTCCTTCCCCGGGACTCTGTGATAC
  CTCAGAAGCCAAAGAGGAGGAAGGTGAACAGCTGACAGGCCCCAGGATAGAGGCCCAGACGTAA
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-RsrII
• ACCN: NM_011066
• Insert Size: 3774 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_011066.3, NP_035196.2
• RefSeq Size: 5845 bp
• RefSeq ORF: 3774 bp
• Locus ID: 18627
• UniProt ID: O54943
• Cytogenetics: 1 D
• Gene Summary: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by Clock/Arntl heterodimers but then represses this upregulation in a feedback loop using Per/Cry heterodimers to interact with Clock/Arntl. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. [provided by RefSeq, Jan 2014]