Camk2a (NM_177407) Mouse Untagged Clone

CAT#: MC206017

Camk2a (untagged) - Mouse calcium/calmodulin-dependent protein kinase II alpha (Camk2a), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Camk2a
• Synonyms: CaMKII; mKIAA0968; R74975
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC031745
  GTCAAGCCGGTTCTCCGTTTGCACTCAGGAGCACGGGCAGGCGAGTGGCCCCTAGTTCTGGGGGCAGCGC TTCAGCATCCCAGCCCTAGTTCCCAGCCTAAAGCCTCGCCTGCCTGCCCAGTGCCAGGATGGCTACCATC ACCTGCACCCGATTCACAGAAGAGTACCAGCTCTTTGAGGAACTGGGAAAGGGAGCCTTCTCTGTGGTGC GCAGGTGTGTGAAGGTGCTGGCTGGTCAGGAGTATGCTGCCAAGATTATCAACACCAAGAAGCTTTCAGC CAGAGATCACCAGAAGCTGGAGCGTGAGGCCCGCATCTGCCGCTTGTTGAAGCACCCCAATATCGTCCGA CTCCATGACAGCATCTCCGAGGAGGGGCACCACTACCTTATCTTCGATCTGGTTACTGGTGGGGAACTGT TTGAAGACATTGTGGCCCGGGAGTATTACAGTGAAGCTGATGCCAGCCACTGTATCCAGCAGATCTTGGA GGCTGTGCTACACTGTCACCAGATGGGGGTGGTGCATCGTGACCTGAAGCCTGAGAATCTGTTGCTGGCC TCGAAGCTCAAGGGCGCTGCTGTGAAGCTGGCAGACTTTGGCCTGGCCATAGAGGTGGAGGGGGAGCAGC AGGCATGGTTTGGGTTCGCAGGGACACCTGGATACCTCTCCCCAGAAGTGCTGAGGAAGGACCCGTACGG GAAGCCCGTGGACCTGTGGGCCTGTGGCGTCATCCTGTATATCTTGCTGGTTGGGTATCCCCCGTTCTGG GATGAAGACCAGCATCGCCTGTACCAGCAGATCAAAGCTGGTGCCTATGATTTCCCATCACCAGAATGGG ACACCGTCACCCCAGAAGCCAAGGATCTGATCAATAAGATGCTGACCATCAACCCGTCCAAACGCATCAC GGCCGCTGAGGCTCTCAAGCACCCATGGATCTCGCACCGCTCCACCGTGGCCTCCTGCATGCACAGACAG GAGACCGTGGACTGCCTGAAGAAGTTCAATGCCAGGAGGAAACTGAAGGGAGCCATCCTCACCACTATGC TGGCCACCAGGAACTTCTCCGGAGGGAAGAGCGGAGGAAACAAGAAGAACGATGGTGTGAAGGAATCTTC TGAGAGCACCAACACCACCATTGAGGACGAAGACACCAAAGTGCGCAAACAGGAAATTATCAAAGTGACA GAGCAGCTGATCGAAGCCATAAGCAATGGAGACTTTGAGTCCTACACGAAGATGTGCGACCCTGGAATGA CAGCCTTTGAACCAGAGGCCCTGGGGAACCTGGTGGAGGGCCTGGACTTTCATCGATTCTATTTTGAAAA CCTGTGGTCCCGGAACAGCAAGCCCGTGCACACCACCATCCTGAACCCTCACATCCACCTGATGGGTGAC GAGTCAGCCTGCATCGCCTATATCCGCATCACTCAGTACCTGGATGCAGGCGGCATACCCCGCACGGCCC AGTCAGAGGAGACCCGCGTCTGGCACCGCAGGGACGGCAAATGGCAGATCGTCCACTTCCACAGATCTGG GGCGCCCTCCGTCCTGCCGCATTGAAGGACCAGGCCAGGGTCCCTGCGTCCTTGCTTCGCAGAGATCCGC TCTTTGTCCGTGGAATGTGGCTGCTGGTTCTCCTTTGGATTTTGCTGGAATTCTCCCTGTCAGATCACCC TACCATTGCCACCTATGTACTCGCGTCACGAAAACCTGCTTGTTCACAGAAGTCGCCACGACATCACAGT GAACAGCCAGCTCTCCCCAGCTCCGTTGCCCAAGCTCTTCCTGCCAGTGGGGACCTTCTTCCGGCTTAAG TACCCAGGGTGCTGGCCCCAGGAACCCCCACCCCCTACCCACTGTTGTTGGCCTAGCCTAGCTTTAGCTA TAGATGGGGCCTCAGCTGTGCAATTGGCAGGAAGTGAGGAAGAGGCAGGCAAGCTGTGTTGAGGGCACCT CTCATCGATTCCTTCTTTCCTGGGGTTCCCCGGGGAAGCTCACACGAGGCCCTCAGTCTCCAAGCCAACC CCTTATGAGGGAGAGTGAGAGAGGAGCCAACGCCAGTGAGCCAGGAACTGCTGCTCTCATCTGCTCTCCT CTGTGTTGGCCTTGCCTTTGACCAGACCATCCGCTACGAGGGGTGGGCTCTACCGCCCAGGTGCCCCACT CACTCTGCCTCAGTCCTCCTGTGAAGTTTGCCTCCAGTGTTGACCCACCCACCCTGCCCTTCAACGTCCT TGGAGAATTCCAGCTTCATCTGTCTGAGAGGAGATTGGAAGGTGTTTCAGGGGCAAAGCAAGCAACATTT AGGTATCACTTCTACTTGGACGCATGCCTTTTTACAGCCAAACTTCCGTGTATTTCGTAAATGGATTTTG CGTTAACGGACATCTATGTGATAACTAGACCTCTCAAGTTTACTGTAAAGAAGAGTCGGATGGGTTGGGA AGTGGGTGGGAAGAGGAGTGAGAGGAAGTTTTAACCCCATTCCAGAGGGTCTTTTTTTTGGGGGGTGTCC CTTCTGGGGGAGGGTGCTTTCTGAGGTGGCCTCACCCCCCAGGGAGCATGGTTTCCTTCCATTATGGTCC CCAAAGTCAGCTGACAAGATTTCTTCCAGAGCCAGCATGACTAACACACAGTGAGTCAGGTCAGGGGAGG CTATCAGGAAGGGGTTATCTAGACTTGGCATCTCTGGAACTGGAGACCTCACTACCCTACTTCCCAGGAA ATCTTTCCCGTATCCTTGTGCTATCTCTCCTCAGCCCAGCCCCCACTCACCACCTTCTAGGCACATTATT CTCATCACCTCTCTCAACTTGGCCAAGCAAGAGTGCCAGAAACTTATTTTCCTACTTCATGCTGAACTTG GCCTGGTGTGCGCTCTATTGTGCTTGCCTGCCTCCCTGGCCTTCCTCGACTCCCCTGCCCCGACATACAC ACACACACACACACACACACACACACGCACACGCACACGCGCGCACACACACACATGCACACGCACATGC ACACACTCACACCACTTCCTTCCACCACTTCCTTCCTCCCCCCTCTCCCTCCCTTTCTCTTTCTCTTCTC TCCCTCTTCCTGGGTTTGGCTCTTGTATGGAATGCTGTATCTCATTCACGGGGATCTCCTGTCTGCACTG TTTTCTTTGCATGACTTTATATGCAGTAAGTATGTTGAAAAACAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_177407
• Insert Size: 1437 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC031745, AAH31745
• RefSeq Size: 3208 bp
• RefSeq ORF: 1437 bp
• Locus ID: 12322
• UniProt ID: P11798
• Cytogenetics: 18 34.41 cM
• Gene Summary: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity). Regulates dendritic spine development. Also regulates the migration of developing neurons (By similarity). Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity (PubMed:23805378).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) is the longest transcript and encodes the longest isoform (2).