C2 Mouse Monoclonal Antibody [Clone ID: OTI12G10]
USD 436.00
USD 200.00
Specifications
Product Data | |
Clone Name | OTI12G10 |
Applications | IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:150 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 469-752 of human C2(NP_000054) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 81 kDa |
Gene Name | complement component 2 |
Database Link | |
Background | Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined. [provided by RefSeq, Mar 2009] |
Synonyms | ARMD14; CO2 |
Reference Data | |
Protein Families | Druggable Genome, Protease, Secreted Protein |
Protein Pathways | Complement and coagulation cascades, Systemic lupus erythematosus |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF807188 | Carrier-free (BSA/glycerol-free) C2 mouse monoclonal antibody,clone OTI12G10 |
USD 600.00 |
|
TA807188AM | C2 mouse monoclonal antibody,clone OTI12G10, Biotinylated |
USD 509.00 |
|
TA807188BM | C2 mouse monoclonal antibody,clone OTI12G10, HRP conjugated |
USD 509.00 |
|
TA807188S | C2 mouse monoclonal antibody,clone OTI12G10 |
USD 200.00 |
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