MDA5 (IFIH1) Rabbit Polyclonal Antibody

CAT#: TA392786

IFIH1 polyclonal antibody

Product Images

Western blot (WB) analysis of IFIH1 polyclonal antibody at 1:500 dilution Lane1:DLD whole cell lysate(40ug) Lane2:Panc1 whole cell lysate(40ug) Lane3:HCT116 whole cell lysate(40ug) Lane4:PC3 whole cell lysate(40ug) Lane5:CT26 whole cell lysate(40ug)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:1000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding Human IFIH1.
• Specificity: IFIH1 polyclonal antibody detects endogenous levels of IFIH1 protein.
• Formulation: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Predicted Protein Size: ~ 135 kDa
• Gene Name: interferon induced with helicase C domain 1
• Database Link:
  Entrez Gene 64135 Human
  UniProt ID Q9BYX4
• Background: IFIH1 (interferon induced with helicase C domain 1), also known as MDA5 (melanoma differentiation-associated protein 5), is one of a family of intracellular proteins known to recognise viral RNA and mediate the innate immune response. IFIH1 is causal in type 1 diabetes based on the protective associations of four rare variants, where the derived alleles are predicted to reduce gene expression or function.
• Synonyms: CADM-140 autoantigen; Clinically amyopathic dermatomyositis autoantigen 140 kDa; Helicard; Helicase with 2 CARD domains; IFIH1; Interferon-induced helicase C domain-containing protein 1; Interferon-induced with helicase C domain protein 1; MDA-5; MDA5; Melanoma differentiation-associated protein 5; Murabutide down-regulated protein; RH116; RIG-I-like receptor 2; RLR-2; RNA helicase-DEAD box protein 116
• Note: For research use only, not for use in diagnostic procedure.