RUNX2 Rabbit Polyclonal Antibody

CAT#: TA385195

RUNX Rabbit polyclonal Antibody

Product Images

Western blot analysis of RUNX1/RUNX2/RUNX3 in Raji and Jurkat lysates using RUNX1/RUNX2/RUNX3 antibody.

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  Western blot analysis of RUNX1/RUNX2/RUNX3 expression in MCF-7, Hela and Molt4 lysates using RUNX1/RUNX2/RUNX3 antibody

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  Western blot analysis of RUNX1/RUNX2/RUNX3 in MOLT4 lysates using RUNX antibody.

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  Immunohistochemistry analysis of paraffin-embedded mouse lung using RUNX1/RUNX2/RUNX3 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Specifications

Product Data

• Applications: FC, IF, IHC, IP, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
  IP: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human RUNX1/RUNX2/RUNX3
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 51kDa
• Gene Name: runt related transcription factor 2
• Database Link:
  Entrez Gene 860 Human
  UniProt ID Q01196
• Background: Swiss-Prot Acc.Q01196,Q13761,Q13950.RUNX2 regulates the transcription of various genes including osteopontin, bone sialoprotein, and osteocalcin via binding to the core site of the enhancers or promoters.RUNX3/AML2 is a member of the Runt family of transcription factors. RUNX3 is important for the suppression of cell proliferation in the gastric epithelium, neurogenesis of the dorsal root ganglia, and T cell differentiation.
• Synonyms: AML3; CBF-alpha-1; CBFA1; CCD; CCD1; MGC120022; MGC120023; OSF-2; OSF2; PEA2aA; PEBP2A; PEBP2A1; PEBP2A2; PEBP2aA; PEBP2aA1