CAMK2A Rabbit Polyclonal Antibody

CAT#: TA383857

CaMKII alpha/delta Rabbit polyclonal Antibody

Product Images

Western blot analysis of CaMKII alpha/delta in NIH3T3/K562 lysates using CaMKII alpha/delta antibody.

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  Western blot analysis of CaMKII alpha/delta in NIH/3T3 and K562 lysates using CaMKII alpha/delta antibody.The lane on the right is blocked with the synthesized peptide.

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  Immunohistochemistry analysis of paraffin-embedded Human brain tissue using CaMK2 alpha/delta antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

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  Immunofluorescence analysis of CaMKII alpha/delta in MCF-7 using CaMK2 alpha/delta antibody. The picture on the right is blocked using the synthesized peptide.

Specifications

Product Data

• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/100-1/300
  IF: 1/200-1/1000
  ELISA: 1/10000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized peptide derived from human CaMK2 alpha/delta. AA range:256-305
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Observed MW (kDa):54
• Gene Name: calcium/calmodulin dependent protein kinase II alpha
• Database Link:
  Entrez Gene 815 Human
  UniProt ID Q9UQM7
• Background: Swiss-Prot Acc.Q9UQM7/Q13557.The product of CAMK2A (calcium/calmodulin dependent protein kinase II alpha) belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for CAMK2A.
• Synonyms: CAMKA; CaMKIINalpha; KIAA0968