TBK1 Rabbit Polyclonal Antibody

CAT#: TA382340

Phospho-TBK1/NAK-S172 Rabbit polyclonal Antibody

Product Images

Western blot analysis of extracts of THP-1 cells, using Phospho-TBK1/NAK-S172 pAb (TA382340) at 1:1000 dilution.THP-1 cells were treated by LPS (1 μg/mL) at 37℃ for 6 hours.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.|Detection: ECL Basic Kit .|Exposure time: 5s.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB,1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho S172
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic phosphorylated peptide around S172 of human TBK1/NAK (NP_037386.1).
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 83kDa
• Gene Name: TANK binding kinase 1
• Database Link:
  Entrez Gene 29110 Human
  UniProt ID Q9UHD2
• Background: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.
• Synonyms: 1200008B05Rik; AI462036; AW048562