SH3GL2 Rabbit Polyclonal Antibody

CAT#: TA365772

SH3GL2 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-3: Human cerebella tissue Mouse brain tissue Human cerebrum tissue lysates Primary antibody: TA365772 (SH3GL2 Antibody) at dilution 1/500 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 3 seconds

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA365772 (SH3GL2 Antibody) at dilution 1/45 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA365772 (SH3GL2 Antibody) at dilution 1/45, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human cerebella tissue, Mouse brain tissue, Human cerebrum tissue lysates
  IHC: 50-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human SH3GL2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 40 kDa
• Gene Name: SH3 domain containing GRB2 like 2, endophilin A1
• Database Link:
  Entrez Gene 6456 Human
  UniProt ID Q99962
• Background: Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes.
• Synonyms: CNSA2; EEN-B1; Endophilin-1; FLJ20276; FLJ25015; SH3D2A; SH3P4