PDHB Rabbit Polyclonal Antibody

CAT#: TA364915

PDHB rabbit polyclonal antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane: Rat heart tissue lysate Primary antibody: TA364915 (PDHB Antibody) at dilution 1/800 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 10 seconds

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA364915 (PDHB Antibody) at dilution 1/160 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA364915 (PDHB Antibody) at dilution 1/160, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA364915 (PDHB Antibody) at dilution 1/160 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA364915 (PDHB Antibody) at dilution 1/160, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Rat heart tissue lysate
  IHC: 150-300
  Positive control: Human prostate cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human PDHB
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 39 kDa
• Gene Name: pyruvate dehydrogenase (lipoamide) beta
• Database Link:
  Entrez Gene 5162 Human
  UniProt ID P11177
• Background: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]
• Synonyms: DKFZp564K0164; PDHE1-B; PHE1B