Suppressor of Fused (SUFU) Rabbit Polyclonal Antibody

CAT#: TA364576

SUFU rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Hela cell lysate Primary antibody: TA364576 (SUFU Antibody) at dilution 1/1150 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 30 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela cell lysate
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human SUFU
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 54 kDa
• Gene Name: SUFU negative regulator of hedgehog signaling
• Database Link:
  Entrez Gene 51684 Human
  UniProt ID Q9UMX1
• Background: The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
• Synonyms: PRO1280; SUFUH; SUFUXL