Cysteine Dioxygenase Type 1 (CDO1) Rabbit Polyclonal Antibody

CAT#: TA349155

Rabbit Polyclonal Anti-CDO1 Antibody

Product Images

Western blot analysis of CDO1 in rat liver tissue lysate with CDO1 antibody at (A) 1 and (B) 2 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: CDO1 antibody was raised against a 19 amino acid peptide near the amino terminus of human CDO1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: CDO1 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 22 kDa; Observed: 24 kDa
• Gene Name: cysteine dioxygenase type 1
• Database Link:
  NP_001792
  Entrez Gene 12583 MouseEntrez Gene 81718 RatEntrez Gene 1036 Human
  UniProt ID Q16878
• Background: CDO1 (cysteine dioxygenase, type I) belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis (1). CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine (1,2). CDO1 exists as a monomer and is expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart (1). CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell (3,4).
• Synonyms: cysteine dioxygenase; cysteine dioxygenase type I; type I

Reference Data

• Protein Pathways: Cysteine and methionine metabolism, Metabolic pathways, Taurine and hypotaurine metabolism