ZIC2 Rabbit Polyclonal Antibody

CAT#: TA339144

Rabbit Polyclonal Anti-ZIC2 Antibody

Product Images

WB Suggested Anti-ZIC2 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate

• 

  Human Skin

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB, IHC
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-ZIC2 antibody: synthetic peptide directed towards the C terminal of human ZIC2. Synthetic peptide located within the following region: EPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGS
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Protein A purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 55 kDa
• Gene Name: Zic family member 2
• Database Link:
  NP_009060
  Entrez Gene 7546 Human
  UniProt ID O95409
• Background: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. [provided by RefSeq, Jul 2008]
• Synonyms: HPE5
• Note: Immunogen Sequence Homology: Human: 100%; Rat: 92%; Pig: 87%; Guinea pig: 87%; Mouse: 85%

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Hedgehog signaling pathway