Cytochrome C (CYCS) Rabbit Polyclonal Antibody

CAT#: TA326782

Rabbit anti-CYCS Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cells, using CYCS antibody.

• 

  Immunohistochemistry of paraffin-embedded Colon cancer using CYCS Antibody.

• 

  Immunohistochemistry of paraffin-embedded human thyroid cancer using CYCS antibody at dilution of 1:200 (200x lens).

• 

  Immunohistochemistry of paraffin-embedded human kidney using CYCS antibody at dilution of 1:200 (200x lens).

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:1000;IHC 1:50 - 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human CYCS
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 12 kDa
• Gene Name: cytochrome c, somatic
• Database Link:
  NP_061820
  Entrez Gene 13063 MouseEntrez Gene 25309 RatEntrez Gene 54205 Human
  UniProt ID P99999
• Background: Cytochrome c is a well conserved electron-transport protein and is part of the respiratory chain localized to mitochondrial intermembrane space. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with procaspase-9 (47 kDa)/Apaf 1. This complex processes caspase-9 from inactive proenzyme to its active form. This event further triggers caspase-3 activation and eventually leads to apoptosis.
• Synonyms: CYC; HCS; THC4

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Huntington's disease, p53 signaling pathway, Parkinson's disease, Pathways in cancer, Small cell lung cancer, Viral myocarditis