PAX6 Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | ELISA, WB |
Reactivities | Human, Mouse, Rat, Xenopus, Zebrafish |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide derived from internal part of Human PAX6 protein |
Specificity | Reacts with the Human 95 kDa PAX6 protein. Cross react with Mouse, Rat, Chicken, Zebrafish, Xenopus laevis and other species due to sequence homology. |
Formulation | 0.1M Tris, 0.1M Glycine and 2% Sucrose State: Purified State: Lyophilized purified antibody Preservative: None |
Reconstitution Method | Restore in distilled water. |
Purification | Affinity Chromatography on Protein A |
Conjugation | Unconjugated |
Storage | Prior to reconstitution store the antibody at -20°C. |
Stability | Shelf life: one year from despatch. |
Gene Name | paired box 6 |
Database Link | |
Background | PAX6 is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. PAX6 is required for the differentiation of pancreatic islet alpha cells and competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. The Pax6-5A isoform appears to function as a molecular switch that specifies target genes. |
Synonyms | Pax-6, Aniridia type II protein, AN2, Oculorhombin |
Reference Data |
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