MRP1 (ABCC1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP17070PU-N

MRP1 (ABCC1) (C-term) rabbit polyclonal antibody

Product Images

Western blot analysis of ABCC1 antibody (C-term) in Ramos cell line lysates (35 ug/lane). ABCC1 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1000.
  Western blot: 1:50 - 1:100.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human ABCC1
• Specificity: This antibody detects ABCC1 / MRP1 at C-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: ATP binding cassette subfamily C member 1
• Database Link:
  Entrez Gene 4363 Human
  UniProt ID P33527
• Background: ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC gene are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.
• Synonyms: Multidrug resistance-associated protein 1, LTC4 transporter
• Note: Molecular weight: 171561 Da