ACVRL1 (C-term) Rabbit Polyclonal Antibody
Other products for "ACVRL1"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ACVRL1. |
Specificity | This antibody recognizes ACVRL1. |
Formulation | PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid purified Ig fraction. |
Concentration | lot specific |
Purification | Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | activin A receptor like type 1 |
Database Link | |
Background | ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. |
Synonyms | ACVRLK1, Activin receptor-like kinase 1, SKR3 |
Note | Calculated MW: 56124 Da |
Reference Data |
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