SKP1 (Center) Rabbit Polyclonal Antibody

CAT#: AP11747PU-N

SKP1 (Center) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of anti-SKP1A in CEM cell line lysate (35 ug/lane). SKP1A (arrow) was detected using the purified Pab (1:60 dilution).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA 1:1,000.
  Western blot 1:100 - 1:500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human SKP1A.
• Specificity: This antibody detects SKP1 at center.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: S-phase kinase-associated protein 1
• Database Link:
  Entrez Gene 6500 Human
  UniProt ID P63208
• Background: SKP1A is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. SKP1A also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor.
• Synonyms: SKP1A, p19skp1, p19A, OCP-2, OCP-II, EMC19, TCEB1L
• Note: Molecular weight: 18527 Da