IRF7 Rabbit Polyclonal Antibody

CAT#: AP05594PU-N

IRF7 rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of whole cell lysate from HEK293 human kidney epithelial cell line probed with Rabbit anti Human IRF7 antibody at 0.5 (A) and 1 (B) ug/ml.

• 

  Immunohistochemical staining of Mouse spleen with Rabbit anti Human IRF7 antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western Blot: 0.5-1.0 µg/ml. Detects a band of approximately 51kDa in 293 whole cell lysate.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: 14 amino acid peptide sequence near the center of Human IRF7.
• Specificity: This antibody detects Human Interferon Regulatory Factor 7 (IRF7). Other species not tested.
• Formulation: PBS
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: interferon regulatory factor 7
• Database Link:
  Entrez Gene 3665 Human
  UniProt ID Q92985
• Background: IRF7 is a 54kD transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production.
  Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.
• Synonyms: IRF-7