CDK1 pThr161 Rabbit Polyclonal Antibody

CAT#: AP01546PU-N

CDK1 pThr161 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of p-CDC2 (pThr161) antibody Cat.-No.: AP01546PU-N in extracts from A2780 cells.

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  Immunohistochemistry (IHC) analyzes of p-CDC2 (pThr161) antibody Cat.-No.: AP01546PU-N in paraffin-embedded human breast carcinoma tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
  Immunohistochemistry on paraffin sections: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: p-CDC2 (pTht161) antibody detects endogenous levels of p-CDC2 protein.
• Formulation: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 34 kDa
• Gene Name: cyclin-dependent kinase 1
• Database Link:
  Entrez Gene 983 Human
  UniProt ID P06493
• Background: The cell cycle in Arabidopsis thaliana mediates organ morphogenesis, cell proliferation and differentiation, and these functions are restricted to the eristems. The cell cycle is controlled by cyclin-dependent kinases, which bind to positive regulators called cyclins. In particular, Arabidopsis B-type cyclin controls cell cycle progression by regulating gene expression late in the G2 and M phases. Expression of cyclin Ds have been shown to increase in response to sucrose. Cdc2 and Cdc2B control cell cycle progression after forming a complex with cyclin. Prolifera and pelota are required for DNA replication and meiotic cell division, respectively.
• Synonyms: CDK1, CDC2, CDC28A, CDKN1, P34CDC2, p34 protein kinase