CCKBR Rabbit Polyclonal Antibody

CAT#: AP01421PU-N

CCKBR rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CCK-BR antibody (Cat.-No.: AP01421PU-N) in Hela whole cell lysate at 1/500 dilution.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of CCK-BR protein. (region surrounding Leu54)
• Formulation: Phosphate buffered saline (PBS), pH~7.2 with 0.05% Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% (by SDS-PAGE)
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~52 kDa
• Gene Name: cholecystokinin B receptor
• Database Link:
  Entrez Gene 887 Human
  UniProt ID P32239
• Background: CCKBR is a G protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. CCKBR is most abundant in brain and stomach but it can also be found in colon, pancreas, thyroid, and various cancers.
• Synonyms: CCKB Receptor, Cholecystokinin type B receptor, CCK-BR, CCKBR, CCKRB, Cholecystokinin-2 receptor, CCK2-R