alpha Actinin (ACTN1) Mouse Monoclonal Antibody [Clone ID: CB11]

CAT#: AM32080PU-N

alpha Actinin (ACTN1) mouse monoclonal antibody, clone CB11, Ig Fraction

Specifications

Product Data

• Clone Name: CB11
• Applications: ELISA, IHC, WB
• Recommended Dilution: Western blotting: 1/1000.
  Immunohistochemical on Frozen Sections.
  Other Immunoassays for cellular and tumor biology.
• Reactivities: Chicken, Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified a-actinin from Chicken gizzard.
  Hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
• Specificity: The antibody clone CB11 is specific to the 100 kD Alpha-Actinin polypeptide and reacts with Human and Chicken cells.
• Formulation: PBS
  State: Ig Fraction
  State: Liquid Ig fraction
  Stabilizer: 1.0% BSA
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
  
• Stability: Shelf life: one year from despatch.
• Gene Name: actinin alpha 1
• Database Link:
  Entrez Gene 87 Human
  UniProt ID P12814
• Background: Alpha-actinin was initially isolated from rabbit skeletal muscle as a factor that induces the gelation of F-actin and promotes the superprecipitation of actomyosin. Alpha actinins are actin-binding proteins that carry out different purposes in different different cell types. In myofibrillar cells, alpha-actinin constitutes a major component of Z-discs in striated muscle and of the functionally analogous dense bodies and dense plaques in smooth muscle. alpha-actinin (alpha A) shares structural homology with spectrin and dystrophin.
• Synonyms: Alpha actinin cytoskeletal isoform, Non-muscle alpha-actinin 1