FOXA2 Mouse Monoclonal Antibody [Clone ID: 7H4B7]

CAT#: AM06359SU-N

FOXA2 mouse monoclonal antibody, clone 7H4B7, Ascites

Product Images

Western blot analysis using FOXA2 mouse mAb against A549 (1) cell lysate.

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  Immunohistochemical analysis of paraffin-embedded human colon cancer (A), gastric cancer (B) and rectal cancer (C) tissues using FOXA2 mouse mAb with DAB staining.

Specifications

Product Data

• Clone Name: 7H4B7
• Applications: IHC, WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.
  Immunohistochemistry on paraffin sections: 1/200 - 1/1000.
  ELISA: 1/10000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of FOXA2 expressed in E. Coli.
• Specificity: This antibody reacts to FOXA2.
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% sodium azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 48 kDa
• Gene Name: forkhead box A2
• Database Link:
  Entrez Gene 3170 Human
  UniProt ID Q9Y261
• Background: FOXA2 (forkhead box A2), also known as HNF3B (hepatocyte nuclear factor 3, beta). It is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA2 has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for FOXA2.
• Synonyms: HNF-3-beta, HNF-3B, TCF3B