C Reactive Protein (CRP) Mouse Monoclonal Antibody [Clone ID: C7]

CAT#: AM03133PU-N

C Reactive Protein (CRP) mouse monoclonal antibody, clone C7, Aff - Purified

Specifications

Product Data

• Clone Name: C7
• Applications: ELISA
• Recommended Dilution: ELISA: The clone C7 has been tested as the detection antibody in a Sandwich ELISA for analysis of C-Reactive Protein in combination with the antibody clone C5 (Cat.-No. AM20202PU-N).
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified Human CRP
• Specificity: The antibody C7 recognizes CRP, an 117 kDa acute phase protein.
  It recognizes antigen both in the presence and in the absence (samples containing EDTA) of Ca²⁺.
• Formulation: Phosphate buffered saline (PBS), pH~7.4
  State: Aff - Purified
  State: Liquid purified Ig fraction from Ascites (> 95% pure by SDS-PAGE)
  Preservative: 15 mM Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C.
  DO NOT FREEZE!
  
• Stability: Shelf life: one year from despatch.
• Gene Name: C-reactive protein, pentraxin-related
• Database Link:
  Entrez Gene 1401 Human
  UniProt ID P02741
• Background: The C-reactive protein (CRP) is a cyclic pentameric pentraxin family acute phase protein compound of five identical noncovalently bound nonglycosylated subunits (each subunit 24 kDa; physiologic CRP molecule 117,5 kDa). CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes occuring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.) and is also believed to play an important role in innate immunity. Patients with elevated basal levels of CRP are at increased risk for hypertension and cardiovascular disease.
• Synonyms: PTX1, C Reactive Protein, Pentraxin-related