Custom Antibody Service

Custom Antibody Development

Custom Antibody Development & Large Scale GMP Manufacturing

OriGene's custom antibody services are a one-stop shop for researchers wanting to develop novel antibodies.

  • Comprehensive Integrated Service: antigen production, antibody engineering, development, purification, validation, and large-scale production (mg to Kgs)
  • Experienced: 25+ years' experience serving pharma, biotech, and academia, developed 15,000+ mouse and rabbit monoclonal antibodies
  • Customer-Centric: Ph.D. level project managers providing timely and expert guidance
  • GMP Manufacturing: Large scale (gms to Kgs) manufacturing available, ISL13485-2016 certified. Find out more.

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Custom Mouse Monoclonal Antibody Development

Features and Benefits

  • Good track record (successful rate > 90%): 15,000+ clones developed
  • Streamline workflow starting from antigen preparation to antibody purification
  • Milestone evaluation & deliveries: you have complete control over the development process. At each checkpoint, you will receive:
    • Phase I: Antigen for immunization (4-8 weeks)
    • Phase II: Two monthly reports, including the ELISA results of serum testing (6-8 weeks)
    • Phase III: Culture supernatants from a minimum of 10 antigen reactive clones along with the ELISA results (4 weeks)
    • Phase IV: 2 mg of purified antibodies per clone from three selected clones, frozen hybridomas (6-8 weeks)
  • Application validations: IHC, ICC, FC, ELISA, Neutralization, WB
  • Specificity validations: ELISA, 10K Protein Microarray (charged service)
  • Convertible to recombinant production
  • Contract GMP Manufacturing available; ideal for assay developers for diagnostics

Custom Rabbit Recombinant Antibody Development

Features and Benefits

  • Experienced: Produced 250+ recombinant antibody clones, proven track record (successful rate > 90%)
  • Streamline workflow starting from antigen preparation to antibody purification
  • Milestone evaluation & deliveries: you have complete control over the development process. At each checkpoint, you will receive:
    • Phase I: Antigen for immunization (4-8 weeks)
    • Phase II: Three monthly reports, including the ELISA results of serum testing (8-12 weeks)
    • Phase III: Culture supernatants from a minimum of 5 antigen reactive clones along with the ELISA results (2 weeks)
    • Phase IV: 1 mg of purified antibodies per clone from three selected clones, antibody sequence information, and expression plasmids (6 weeks)
  • Application validations: ELISA, WB, ICC, IF, IHC, FC, Neutralization
  • Specificity validations: ELISA, 10K Protein Microarray (charged service)
  • Contract GMP Manufacturing available; ideal for assay developers for diagnostics

In order to expedite your sequential findings after major scientific breakthroughs, OriGene enables rabbit polyclonal antibody services that fast deliver high titer antisera in three months.

Custom Rabbit Polyclonal Antibody Development

Features and Benefits

  • Antigen preparation supported by OriGene protein scientists: shortening the lead time before antibody development
  • Blood is withdrawn from two immunized animals after three boosters: ensure collecting the antisera of high titer and high avidity
  • Monthly written reports including ELISA testing results: transparent processes in antibody development
  • Application validation service is available
  • Large scale, ISO 13485:2016 certified production available

Features & Benefits

SDIX, an OriGene company, has over 30 years of OEM antibody production experience and is a trusted partner for diagnostic, biotech, pharmaceutical, and antibody reagent manufacturers worldwide. SDIX offers the highest level of cGMP compliance, quality products, and customer service. Our capabilities are as follows.

Large Scale GMP Monoclonal Manufacturing Services

  • Cell line optimization for antibody production
  • Large scale (mg to kg) antibody productuion from customer supplied cell lines (in vivo and in vitro)
  • Cell storage and banking
  • Bioprocessing (monoclonal)
  • Monoclonal FAQ

Large Scale Polyclonal Antibody Production

  • Protocol Development thru Large Scale Production
  • Bioprocessing (polyclonal)
  • Capabilities and Services
  • Polyclonal FAQ
  • Antibody protocols by species

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