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RNAi Substrates - shRNA, siRNA & miRNA


RNA Interference (RNAi) is a gene-silencing process that targets mRNA hence lowering protein expression. The key RNAi substrates regulating this process are shRNA, siRNA and miRNA. (Learn More about RNAi substrates).

OriGene provides comprehensive and innovative RNAi tools for various applications:

Key Features:

  • Genome wide coverage for human, mouse & rat genes
  • Higher potency with minimal interferon response
  • Performance guaranteed!

Human, mouse & rat. Lentiviral shRNA - new!
MicroRNA Expression Plasmids
Genome-wide coverage for human & mouse miRNA
Human, mouse, rat
Guaranteed knockdown Promotion
MicroRNA qPCR Assays
SYBR Green qPCR assays for miRNA expression profiling
Exact shRNA
Design against any species, any variant.
3'UTR Clones as MicroRNA Target
Study microRNA target and function

Benefits of choosing different RNAi substrates offered by OriGene based on research application

  siRNA shRNA miRNA Expression
Gene-Specific Knockdown Yes Yes No, regulates multiple genes
Transient Transfection Yes Yes Yes
Stable Transfection No Yes Yes
Infection No Yes No
Performance Guarantee Yes Yes Fully Sequenced
Renewable RNAi Resource No Yes Yes
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