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OriGene in recent publications
Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease Bioorg. Med. Chem. Lett. 2017 [ENGASE]

The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARγ Life Sci. 2017 [OLR1]

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 [HSPA5]

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 [ERN1]

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227 Categories

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NameCount
ABC transporters103
Acute myeloid leukemia196
Adherens junction293
Adipocytokine signaling pathway198
Adult stem cells188
Alanine, aspartate and glutamate metabolism82
Allograft rejection78
alpha-Linolenic acid metabolism34
Alzheimer's disease428
Amino sugar and nucleotide sugar metabolism122
Aminoacyl-tRNA biosynthesis85
Amyotrophic lateral sclerosis (ALS)174
Androgen and estrogen metabolism76
Antigen processing and presentation199
Apoptosis292
Arachidonic acid metabolism126
Arginine and proline metabolism140
Arrhythmogenic right ventricular cardiomyopathy (ARVC)247
Ascorbate and aldarate metabolism46
Asthma53
Autoimmune thyroid disease104
Axon guidance398
B cell receptor signaling pathway225
Basal cell carcinoma130
Basal transcription factors72
Base excision repair97
beta-Alanine metabolism47
Biosynthesis of unsaturated fatty acids45
Biotin metabolism9
Bladder cancer155
Butanoate metabolism67
C21-Steroid hormone metabolism20
Caffeine metabolism19
Calcium signaling pathway536
Cancer stem cells92
Cardiac muscle contraction193
Cell adhesion molecules (CAMs)326
Cell cycle355
Chemokine signaling pathway494
Chondroitin sulfate biosynthesis39
Chronic myeloid leukemia224
Circadian rhythm - mammal33
Citrate cycle (TCA cycle)83
Colorectal cancer257
Complement and coagulation cascades169
Cyanoamino acid metabolism34
Cysteine and methionine metabolism92
Cytokine-cytokine receptor interaction596
Cytosolic DNA-sensing pathway137
D-Arginine and D-ornithine metabolism2

 

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