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Home Recombinant Human Proteins All LGR5 Proteins

LGR5 (NM_003667) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP700187 Purified recombinant protein of Homo sapiens leucine-rich repeat containing G protein-coupled receptor 5 (LGR5), residues 447-561aa, with C-terminal Fc tag, expressed in HEK293 cells., 20 ug (Larger pack size?) $680 In Stock
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC212825, encoding the extracellular domain (His447 - Arg561) of human leucine-rich repeat containing G protein-coupled receptor 5 (LGR5)
Tag:C-terminal Fc Predicted MW:38 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:DPBS, 10% glycerol
Protein Families: GPCRTransmembraneDruggable Genome
Protein Pathways:
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_003658 RefSeq Size: 2880 RefSeq ORF: 2721
LocusID: 8549 Cytogenetic: 12q21.1  
Synonyms : FEX; GPR49; GPR67; GRP49; HG38
Summary: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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