Grin2a (NM_008170) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR227135L3V

  • LentiORF®

Lenti ORF particles, Grin2a (Myc-DDK-tagged) - Mouse glutamate receptor, ionotropic, NMDA2A (epsilon 1) (Grin2a), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Lentiviral Particles: DDK w/ Puro mGFP w/ Puro



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USD 2,428.00

7 Weeks*

Size
    • 200 ul

Product Images

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Specifications

Product Data
Type Mouse Tagged ORF Clone
Tag Myc-DDK
Symbol Grin2a
Synonyms GluN2A; NMDAR2A; NR2A
Mammalian Cell Selection Puromycin
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_008170
ORF Size 4392 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR227135).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_008170.2
RefSeq Size 4512 bp
RefSeq ORF 4395 bp
Locus ID 14811
UniProt ID P35436
Cytogenetics 16 5.28 cM
Gene Summary Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium (PubMed:1374164). Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kinetics than channels formed by GRIN1 and GRIN2B (By similarity). Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning (PubMed:7816096, PubMed:8987814).[UniProtKB/Swiss-Prot Function]

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