PER1 (BC028207) Human Untagged Clone

CAT#: SC122249

(untagged)-Homo sapiens, Similar to period homolog 1 (Drosophila), clone MGC:40009 IMAGE:5215552, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PER1
• Synonyms: hPER; PER; RIGUI
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC028207 edited
  GTGCGCGCCGAGCGGTACTGGCTGTGATCGAACTTCTCAACCCTCAGAGACTTAGATCTT
  CCACCTCACTCCCTCAGCCAAGCCTCCAGGCCCCCTCGTGCATCCGTGGTGGCCTCTCTG
  CCTTCTCTGTTCTGTTCTCCCCATGGCCCAGACATGAGTGGCCCCCTAGAAGGGGCTGAT
  GGGGGAGGGGACCCCAGGCCTGGGGAATCATTTTGTCCTGGGGGCGTCCCATCCCCTGGG
  CCCCCACAGCACCGGCCTTGCCCAGGCCCCAGCCTGGCCGATGACACCGATGCCAACAGC
  AATGGTTCAAGTGGCAATGAGTCCAACGGGCATGAGTCTAGAGGCGCATCTCAGCGGAGC
  TCACACAGCTCCTCCTCAGGCAACGGCAAGGACTCAGCCCTGCTGGAGACCACTGAGAGC
  AGCAAGAGCACAAACTCTCAGAGCCCATCCCCACCCAGCAGTTCCATTGCCTACAGCCTC
  CTGAGTGCCAGCTCAGAGCAGGACAACCCGTCCACCAGTGGCTGCAGCAGTGAACAGTCA
  GCCCGGGCAAGGACTCAGAAGGAACTCATGACAGCACTTCGAGAGCTCAAGCTTCGACTG
  CCGCCAGAGCGCCGGGGCAAGGGCCGCTCTGGGACCCTGGCCACGCTGCAGTACGCACTG
  GCCTGTGTCAAGCAGGTGCAGGCCAACCAGGAATACTACCAGCAGTGGAGCCTGGAGGAG
  GGCGAGCCTTGCTCCATGGACATGTCCACCTATACCCTGGAGGAGCTGGAGCACATCACG
  TCTGAGTACACACTTCAGAACCAGGATACCTTCTCAGTGGCTGTCTCCTTCCTGACGGGC
  CGAATCGTCTACATTTCGGAGCAGGCAGCCGTCCTGCTGCGTTGCAAGCGGGACGTGTTC
  CGGGGTACCCGCTTCTCTGAGCTCCTGGCTCCCCAGGATGTGGGAGTCTTCTATGGTTCC
  ACTGCTCCATCTCGCCTGCCCACCTGGGGCACAGGGGCCTCAGCAGGTTCAGGCCTCAGG
  GACTTTACCCAGGAGAAGTCCGTCTTCTGCCGTATCAGAGGAGGTCCTGACCGGGATCCA
  GGGCCTCGGTACCAGCCATTCCGCCTAACCCCGTATGTGACCAAGATCCGGGTCTCAGAT
  GGGGCCCCTGCACAGCCGTGCTGCCTGCTGATTGCAGAGCGCATCCATTCGGGTTACGAA
  GCTCCCCGGATACCCCCTGACAAGAGGATTTTCACTACGCGGCACACACCCAGCTGCCTC
  TTCCAGGATGTGGATGAAAGGGCTGCCCCCCTGCTGGGCTACCTGCCCCAGGACCTCCTG
  GGGGCCCCAGTGCTCCTGTTCCTGCATCCTGAGGACCGACCCCTCATGCTGGCTATCCAC
  AAGAAGATTCTGCAGTTGGCGGGCCAGCCCTTTGACCACTCCCCTATCCGCTTCTGTGCC
  CGCAACGGGGAGTATGTCACCATGGACACCAGCTGGGCTGGCTTTGTGCACCCCTGGAGC
  CGCAAGGTAGCCTTCGTGTTGGGCCGCCACAAAGTACGCACGGCCCCCCTGAATGAGGAC
  GTGTTCACTCCCCCGGCCCCCAGCCCAGCTCCCTCCCTGGACACTGATATCCAGGAGCTG
  TCAGAGCAGATCCACCGGCTGCTGCTGCAGCCCGTCCACAGCCCCAGCCCCACGGGACTC
  TGTGGAGTCGGCGCCGTGACATCCCCAGGCCCTCTCCACAGCCCTGGGTCCTCCAGTGAT
  AGCAACGGGGGTGATGCAGAGGGGCCTGGGCCTCCTGCGCCACTACAGGCACGTTCAAGG
  CCAAGGCCCTTCCCTGCCAATCCCCAGACCCAGAGCTGGAGGCGGGTTCTGCTCCCGTCC
  AGGCCCCACTAGCCTTGGTCCCTGAGGAGGCCGAGAGGAAAGAAGCCTCCAGCTGCTCCT
  ACCAGCAGATCAACTGCCTGGACAGCATCCTCAGGTACCTGGAGAGCTGCAACCTCCCCA
  GCACCACTAAGCGTAAATGTGCCTCCTCCTCCTCCTATACCACCTCCTCAGCCTCTGACG
  ACGACAGGCAGAGGACAGGTCCAGTCTCTGTGGGGACCAAGAAAGACATCATCATGATGG
  AGGACCTGCCTGGTCTAGCCCCAGGCCCAGCCCCCAGCCCAGCCCCCAGCCCCACAGTAG
  CCCCTGACCCAGCCCCAGACGCCTACCGTCCAGTGGGGCTGACCAAGGCCGTGCTGTCCC
  TGCACACGCAGAAGGAAGAGCAAGCCTTCCTCAGCCGCTTCCGAGACCTGGGCAGGCTGC
  GTGGACTCGACAGCTCTTCCACAGCTCCCTCAGCCCTTGGCGAGCGAGGTAGCCACCTGG
  GGCCTCCTGGAGCCTGCCCTCTGCCCAGTCTAGGACTGGATTGTTGGGGGGTGGGTCTTA
  AGGGAGGTGTTTCTGCTCCAGGGACCCAGGCTGGTGTTGCTTCCACCACTAGGCCCTGCC
  TAGGGACAGGCCCCTCGCTAGCTTCTCCCCACTAGGATGGGGTTCCGGGCTGCAGCCAGA
  GGAGGGCAGCCTGGGGGGATGGCACTGGGATGGGCAGGCAGAGGTGCTGTCTCCAGGTAA
  GCGACTTCAGGCCTAGCCTGGGGGCAGGGGCAGGAAGTATGCCCACTTAGGAGTCAGTTG
  TCACTGATGAAGAGACATGCATAGATTCTGGGCCAACTCTGGGTGGGGTCTGGGCTTCAA
  GGGCAGGTGGAAGGCAGCCCCTCCAGGTGCCTGAGGGAGATCCCCTGCAGGCAGACGCAG
  GACTCAGGACTGGGCTTTCCAGCCCCACTCTTCACTCCATTGCAAGCTAGGCAGAATACG
  GCCTCGATGGGCAGGAGGAATGCCTAGGCTGGCAGTGCCCACAGGAGTTTGGCGGACCAG
  AGCCATCTGTCCATGTGTCCATGGACTCACCCTGCTTCCTCCATCTGCCAGCATGCCTCC
  ATCTTCCGCACACCCCCAGCTCGACCCCTCGTGTAACCTCTCCCTGGCCTTGTTCCTTTC
  TCAATAAATCCCCTTGTCCCTGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC028207 unedited
  CTATTTTGTATACGACTCATATAGGCGGCCGCGAATTCCCGGGATGTGCGCGCCGAGCGG
  TACTGGCTGTGATCGAACTTCTCAACCCTCAGAGACTTAGATCTTCCACCTCACTCCCTC
  AGCCAAGCCTCCAGGCCCCCTCGTGCATCCGTGGTGGCCTCTCTGCCTTCTCTGTTCTGT
  TCTCCCCATGGCCCAGACATGAGTGGCCCCCTAGAAGGGGCTGATGGGGGAGGGGACCCC
  AGGCCTGGGGAATCATTTTGTCCTGGGGGCGTCCCATCCCCTGGGCCCCCACAGCACCGG
  CCTTGCCCAGGCCCCAGCCTGGCCGATGACACCGATGCCAACAGCAATGGTTCAAGTGGC
  AATGAGTCCAACGGGCATGAGTCTAGAGGCGCATCTCAGCGGAGCTCACACAGCTCCTCC
  TCAGGCAACGGCAAGGACTCAGCCCTGCTGGAGACCACTGAGAGCAGCAAGAGCACAAAC
  TCTCAGAGCCCATCCCCACCCAGCAGTTCCATTGCCTACAGCCTCCTGAGTGCCAGCTCA
  GAGCANGACAACCCGTCCACCAGTGGCTGCAGCAGTGAACAGTCAGCCCGGGCAAGGACT
  CAGAAGGAACTCATGACAGCACTTCGAGAGCTCAAGCTTCGACTGCCGNCAGAGCGCCGG
  GGCAAGGGCCGCTCTGGGACCCTGGCCACGCTGCAGTACGCACTGGCCTGTGTCAAGCAG
  GTGCAGGCCCACCCAGGATACTAACAGCAGTGGAGCCTGGAGGAGGGNCGAGCCTTGCTC
  CATGGACATGTCCACCTTTCCCTGGAAGAACTGGACCACATCACGTCTGATTCCCCCTTC
  AAAACCAGGATACCTTCTAAAGGGCTGGCCCCTTCCTGACCGGCGGAATCTTCTAACTTT
  CGGAACAGGCAACCTTCCTGTGG
  
• Restriction Sites: Please inquire
• ACCN: BC028207
• Insert Size: 3076 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC028207.1
• RefSeq Size: 3076 bp
• Locus ID: 5187
• Cytogenetics: 17p13.1
• Protein Families: Druggable Genome
• Protein Pathways: Circadian rhythm - mammal
• Gene Summary: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described. [provided by RefSeq, Jan 2014]