Aldehyde dehydrogenase 10 (ALDH3A2) (NM_000382) Human Untagged Clone

CAT#: SC119943

ALDH3A2 (untagged)-Human aldehyde dehydrogenase 3 family, member A2 (ALDH3A2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Aldehyde dehydrogenase 10
• Synonyms: ALDH10; FALDH; SLS
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119943 sequence for NM_000382 edited (data generated by NextGen Sequencing)
  ATGGAGCTCGAAGTCCGGCGGGTCCGACAGGCGTTCCTGTCCGGCCGGTCGCGACCTCTG
  CGGTTTCGGCTGCAGCAGCTGGAGGCCCTGCGGAGGATGGTGCAGGAGCGCGAGAAGGAT
  ATCCTGACGGCCATCGCCGCCGACCTGTGCAAGAGTGAATTCAATGTGTACAGTCAGGAA
  GTCATTACTGTCCTTGGGGAAATTGATTTTATGCTTGAGAATCTTCCTGAATGGGTTACT
  GCTAAACCAGTTAAGAAGAACGTGCTCACCATGCTGGATGAGGCCTATATTCAGCCACAG
  CCTCTGGGAGTGGTGCTGATAATCGGAGCTTGGAATTACCCCTTCGTTCTCACCATTCAG
  CCACTGATAGGAGCCATCGCTGCAGGAAATGCTGTGATTATAAAGCCTTCTGAACTGAGT
  GAAAATACAGCCAAGATCTTGGCAAAGCTTCTCCCTCAGTATTTAGACCAGGATCTCTAT
  ATTGTTATTAATGGTGGTGTTGAGGAAACCACGGAGCTCCTGAAGCAGCGATTTGACCAC
  ATTTTCTATACGGGAAACACTGCGGTTGGCAAAATTGTCATGGAAGCTGCTGCCAAGCAT
  CTGACCCCTGTGACTCTTGAACTGGGAGGGAAAAGTCCATGTTATATTGATAAAGATTGT
  GACCTGGACATTGTTTGCAGACGCATAACCTGGGGAAAATACATGAATTGTGGCCAAACC
  TGCATTGCACCCGACTATATTCTCTGTGAAGCATCCCTCCAAAATCAAATTGTATGGAAG
  ATTAAGGAAACAGTGAAGGAATTTTATGGAGAAAATATAAAAGAGTCTCCTGATTATGAA
  AGGATCATCAATCTTCGTCATTTTAAGAGGATACTAAGTTTGCTTGAAGGACAAAAGATA
  GCTTTTGGTGGGGAGACTGATGAGGCCACACGCTACATAGCCCCAACAGTACTTACCGAT
  GTTGATCCTAAAACCAAGGTGATGCAAGAAGAAATTTTTGGACCAATTCTTCCAATAGTG
  CCTGTGAAAAATGTAGATGAGGCCATAAATTTCATAAATGAACGTGAAAAGCCTCTGGCT
  CTTTATGTATTTTCGCATAACCATAAGCTCATCAAACGGATGATTGATGAGACATCCAGT
  GGAGGTGTCACAGGCAATGACGTCATTATGCACTTCACGCTCAACTCTTTCCCATTTGGA
  GGAGTGGGTTCCAGTGGGATGGGAGCTTATCACGGAAAACATAGTTTTGATACTTTTTCT
  CATCAGCGTCCCTGTTTATTAAAAAGTTTAAAGAGAGAAGGTGCTAACAAACTCAGATAT
  CCTCCCAACAGCCAGTCAAAGGTGGATTGGGGAAAATTTTTTCTCTTGAAACGGTTCAAC
  AAAGAAAAACTCGGTCTCCTGTTGCTCACTTTCCTGGGTATTGTAGCCGCTGTGCTTGTC
  AAGGCTGAATATTACTGA
  
  Clone variation with respect to NM_000382.2
  1446 a=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000382 unedited
  NGGGTCATATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACCAGGCGGCTGAG
  CGAGCGAGCCCTGGGCGAGTGAATTGTGGCTGTGGGTTGACGGTGGAGACACCCCCCGGA
  GGGAGGCGGAGGGAAGGGAGGCGAGGCCTGCACCTGCATGCTTCCCGCCTCCCACTCCCC
  AGCGCCCCCGGACCGTGCAGTTCTCTGCAGGACCAGGCCATGGAGCTCGAAGTCCGGCGG
  GTCCGACAGGCGTTCCTGTCCGGCCGGTCGCGACCTCTGCGGTTTCGGCTGCAGCAGCTG
  GAGGCCCTGCGGAGGATGGTGCAGGAGCGCGAGAAGGATATCCTGACGGCCATCGCCGCC
  GACCTGTGCAAGAGTGAATTCAATGTGTACAGTCAGGAAGTCATTACTGTCCTTGGGGAA
  ATTGATTTTATGCTTGAGAATCTTCCTGAATGGGTTACTGCTAAACCAGTTAAGAAGAAC
  GTGCTCACCATGCTGGATGAGGCCTATATTCAGCCACAGCCTCTGGGAGTGGTGCTGATA
  ATCGGAGCTTGGAATTACCCCTTCGTTCTCACCATTCAGCCACTGATAGGAGCCATCGCT
  GCANGAAATGCTGTGATTATAAAGCCTTCTGAACTGAGTGAAAATACAGNCAAGGATCTT
  GCAAAGCTTCTCCCTCAGTATTTAGACCAGGATCTCTATATTGTTATTAATGGNGGGTGG
  TGGAGGGAACCACGGAAGCTCCTGAAGCACCGATTTGACCCCATTTTCTATACGGGAAAA
  CCCTGCCGGTTGGCAAAATTGTCATGGAAACTTGCTTGCAAGCATCTGACCCCCGGGACT
  CTTGACCTGGGAGGGAAAAATCCCTTGTTTTTTTGTTAAAGATT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000382 unedited
  CTTGGACGCGGCCGCAATCTANAATCGAGTTTTTTTTTTTTTTTTTTTTGATAAAGACAT
  AAAATGATTTATAGTTGGGGAGAATTTATGATCAAAGGATTGTCTCCAATAGGGTATATC
  TGAGGTTCCATACCAGGAGCGTCATTAAAATTGATGCCAATTTTATGAAATATGTTCATT
  TTGAAGCAGATGTGTATTAGTAGACAAGCCAATAATTTAAACATACTCAATGAAAATTCC
  ATAGTGCAATTTTATCTAAGGTATTTTATGATTACTCTCTTAGAGCCACAGTTTTAAGCA
  GCTTTTTCCTAAACTAGGCTCGTTATTAATTTTCAACACTTCATACTATGATGAAGACAT
  CACATACTTTAGACAGCCTTAATAGAACAAATTATTCAACAAAGTTGATTATACGTTCTA
  TAAAGTAAATCACATTCTCTCATTGAGTGAGCTGAGTCTTTCTGAGTGTGGGGACAGAGT
  CCCTGCAGTCAGGAGCTCCAAGGCATAGAACTGCCTGCCCTGCTCTGTCCAGCAGGTAAT
  GCTGCATTCCACAGGCCTCTTCTTCAGCCTTGCCCACTCAGCAGAGTACCTCAGGTTGTG
  ACCATGAACGACTGATGAGAGTAACTTCTGACTTGCTCAGGGGATCCTCTTGCCATCAAT
  TCCCTTCAGTATGACCAACCGCAGTGGCTTACTCGCTTCTTGGCAGACCATCCACCATCT
  GTCTGCCCATGATGCTCTCAAACCCAAAAGTCTAATATCCCAGCCCTCTTTGTCTGTGAG
  AGGAAAGGGCTCCCTCACTTTAAGNTCTGTAGGGCTATCAGAAAGGGATCTCTCTATAGT
  TTCAAAAGTGAAATTTACTTGGCCTACAGAAATAGAAACTACCGAATTGTTCTGGAAAAC
  CACTACCTGCACCTTAAGGCCCTGAAGAGATAANATGTTATAATACTTTATACAGATTTT
  TATTGTTTCGGAACGGGCCTGCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000382
• Insert Size: 3370 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000382.2, NP_000373.1
• RefSeq Size: 3702 bp
• RefSeq ORF: 1458 bp
• Locus ID: 224
• UniProt ID: P51648
• Cytogenetics: 17p11.2
• Domains: aldedh
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation
• Gene Summary: Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks an alternate segment in the 3' coding region compared to variant 1. Isoform 2 has a shorter and different C-terminus, compared to isoform 1.