IRF7 (NM_004029) Human Untagged Clone

CAT#: SC109354

IRF7 (untagged)-Human interferon regulatory factor 7 (IRF7), transcript variant b

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IRF7
• Synonyms: IMD39; IRF-7; IRF-7H; IRF7A; IRF7B; IRF7C; IRF7H
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004029 edited
  GAATTCGGCACGAGGCTTCCCGTCCCGGCGGCTCTGGCACCCAGGGTCCGGCCTGCGCCT
  TCCCGCCAGGCCTGGACACTGGTTCAACACCTGTGACTTCATGTGTGCGCGCCGGCCACA
  CCTGCAGTCACACCTGTAGCCCCCTCTGCCAAGAGATCCATACCGAGGCAGCGTCGGTGG
  CTACAAGCCCTCAGTCCACACCTGTGGACACCTGTGACACCTGGCCACACGACCTGTGGC
  CGCGGCCTGGCGTCTGCTGCGACAGGAGCCCTTACCTCCCCTGTTATAACACCTGACCGC
  CACCTAACTGCCCCTGCAGAAGGAGCAATGGCCTTGGCTCCTGAGAGGGCAGCCCCACGC
  GTGCTGTTCGGAGAGTGGCTCCTTGGAGAGATCAGCAGCGGCTGCTATGAGGGGCTGCAG
  TGGCTGGACGAGGCCCGCACCTGTTTCCGCGTGCCCTGGAAGCACTTCGCGCGCAAGGAC
  CTGAGCGAGGCCGACGCGCGCATCTTCAAGGCCTGGGCTGTGGCCCGCGGCAGGTGGCCG
  CCTAGCAGCAGGGGAGGTGGCCCGCCCCCCGAGGCTGAGACTGCGGAGCGCGCCGGCTGG
  AAAACCAACTTCCGCTGCGCACTGCGCAGCACGCGTCGCTTCGTGATGCTGCGAGATAAC
  TCGGGGGACCCGGCCGACCCGCACAAGGTGTACGCGCTCAGCCGGGAGCTGTGCTGGCGA
  GAAGGCCCAGGCACGGACCAGACTGAGGCAGAGGCCCCCGCAGCTGTCCCACCACCACAG
  GGTGGGCCCCCAGGGCCATTCCTGGCACACACACATGCTGGACTCCAAGCCCCAGGCCCC
  CTCCCTGCCCCAGCTGGTGACAAGGGGGACCTCCTGCTCCAGGCAGTGCAACAGAGCTGC
  CTGGCAGACCATCTGCTGACAGCGTCATGGGGGGCAGATCCAGTCCCAACCAAGGCTCCT
  GGAGAGGGACAAGAAGGGCTTCCCCTGACTGGGGCCTGTGCTGGAGGCGAGGCCGCGGCC
  CCAGAGTCCCCGCACCAGGCAGAGCCGTACCTGTCACCCTCCCCAAGCGCCTGCACCGCG
  GTGCAAGAGCCCAGCCCAGGGGCGCTGGACGTGACCATCATGTACAAGGGCCGCACGGTG
  CTGCAGAAGGTGGTGGGACACCCGAGCTGCACGTTCCTATACGGCCCCCCAGACCCAGCT
  GTCCGGGCCACAGACCCCCAGCAGGTAGCATTCCCCAGCCCTGCCGAGCTCCCGGACCAG
  AAGCAGCTGCGCTACACGGAGGAACTGCTGCGGCACGTGGCCCCTGGGTTGCACCTGGAG
  CTTCGGGGGCCACAGCTGTGGGCCCGGCGCATGGGCAAGTGCAAGGTGTACTGGGAGGTG
  GGCGGACCCCCAGGCTCCGCCAGCCCCTCCACCCCAGCCTGCCTGCTGCCTCGGAACTGT
  GACACCCCCATCTTCGACTTCAGAGTCTTCTTCCAAGAGCTGGTGGAATTCCGGGCACGG
  CAGCGCCGTGGCTCCCCACGCTATACCATCTACCTGGGCTTCGGGCAGGACCTGTCAGCT
  GGGAGGCCCAAGGAGAAGAGCCTGGTCCTGGTGAAGCTGGAACCCTGGCTGTGCCGAGTG
  CACCTAGAGGGCACGCAGCGTGAGGGTGTGTCTTCCCTGGATAGCAGCAGCCTCAGCCTC
  TGCCTGTCCAGCGCCAACAGCCTCTATGACGACATCGAGTGCTTCCTTATGGAGCTGGAG
  CAGCCCGCCTAGAACCCAGTCTAATGAGAACTCCAGAAAGCTGGAGCAGCCCACCTAGAG
  CTGGCCGCGGCCGCCCAGTCTAATAAAAAGAACTCCAGAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004029 unedited
  GGGTCAAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCTTCCCGTC
  CCGGCGGCTCTGGCACCCAGGTCCGGCCTGCGCCTTCCCGCCAGGCCTGGACACTGGTTC
  AACACCTGTGACTTCATGTGTGCGCGCCGGCCACACCTGCAGTCACACCTGTAGCCCCCT
  CTGCCAAGAGATCCATACCGAGGCAGCGTCGGTGGCTACAAGCCCTCAGTCCACACCTGT
  GGACACCTGTGACACCTGGCCACACGACCTGTGGCCGCGGCCTGGCGTCTGCTGCGACAG
  GAGCCCTTACCTCCCCTGTTATAACACCTGACCGCCACCTAACTGCCCCTGCAGAAGGAG
  CAATGGCCTTGGCTCCTGAGAGGGCAGCCCCACGCGTGCTGTTCGGAGAGTGGCTCCTTG
  GAGAGATCAGCAGCGGCTGCTATGAGGGGCTGCAGTGGCTGGACGAGGCCCGCACCTGTT
  TCCGCGTGCCCTGGAAGCACTTCGCGCGCAAGGACCTGAGCGAGGCCGACGCGCGCATCT
  TCAAGGCCTGGGCTGTGGCCCGCGGCAGGTGGCCGCCTAGCAGCAGGGGAGGTGGCCCGC
  CCCCGAGGCTGAGACTGCGGAGCGCGCCCGCTGGAAAACCAACTTCCGCTGCGCACTGCG
  CAGCACGCGTCGCTTTGTGATGCTGCGAGATAACTCGGGGGACCCGGCCGACCCGCACAA
  AGTGTACGCGCTCACCCGGAACCTGNGCTGGCGAAAAAGTCCAGGCCCGGACCAGACTGA
  GGCAGAGGCCCCCGCAGCTGTCCACCACCACAGGGTGGGCCCCCCAGGGCCATTCCTGAC
  ACACCCCCATGCTTGGATTCCAAGCCCCCAGGCCCCCTTCCTTGCCCAAANTGGGGAAAG
  GGGGGACCTCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004029 unedited
  ACGCCCTTCTAAAGTCGAGCCCTTTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTCGGGAGTTCTTTTTATTAAACTGGGCGGCCGGGGCCATCT
  TTAGGGGGGCTGCCCCAGCTTTTTGGAGTTCTAATTAAACTGGGTTTTAGGCGGGCTGCT
  CCACCTCCATAAGGAACCCCTCGATGTCCCCATAAAGGCTGTGGGCCCTGGACAGGCAAA
  GGCTGAGGCTGCTGCTTTCCAGGGAAAACACACCCTCACCCTGCGGGCCCTTTAGGGGCA
  CTCGGAACAGCCAGGGTTCCAGTTTCACCAAAACCAGGCTTTTTTCCTTGGGCCTCCCAT
  TTGACAGGTCCTGCCCGAACCCCATGTAAATGGTATAGCGGGGGGAGCCACGGGCCTGCC
  GTGCCCGGAATTCCACCACCTTTTGGAAAAAAACCCTGAAGCCAAAAATGGGGGGGTCAC
  ATTTCCCAGGCATCAGCCACCCTGGGGTGGAGGGGCCTGCGGACCCCTGGGGCCCCTCAC
  CCCCTACACACCTTGTTCTGCTCCTCGCCCGGGCTCACAGTTGGGCCTCCGCAAACTCCA
  GTGGCCCCTCAGGGGTTCCTTTCCCCTATTGCTTTTTCCGTTCACCCTCTCACCACCCTT
  ATTCCCAACTCTTCCCTTCACTTATTCTTTATTTCCTTCTTTCATCCTCTCTTTCCACTT
  TTTCCTCCTCCCCACACTCTCATCCTCCTCTTTTTTATCCCTATTCACTCCCTCTTATTC
  TTCTACTCTCCTCTCCCTTACACTCCCCACACCCTCTCCCCCTCCTCTCCCTTCTCCTTC
  TCCCCTCTCCTCCTCCCCTCTATCCCCCTTCCACCCCACTCTCTACCTCCCCTTCTCCCC
  CCAGCCTCCCCTCATCACTCTTCTTTTTTTTCTTTAATTCCTTCCCCCCTTCTTCTACCT
  CTTTTTCTTTTCTCTTTACTCCTCACCATTCACCCTCCAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004029
• Insert Size: 1950 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004029.1, NP_004020.1
• RefSeq Size: 1816 bp
• RefSeq ORF: 1425 bp
• Locus ID: 3665
• UniProt ID: Q92985
• Cytogenetics: 11p15.5
• Domains: IRF
• Protein Families: Transcription Factors
• Protein Pathways: Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
• Gene Summary: IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (b) has an alternate exon structure in the 5' coding region and lacks an alternate in-frame exon, compared to variant d. The resulting isoform (b) is shorter and has a distinct N-terminus compared to isoform d.