Monoamine Oxidase B (MAOB) (NM_000898) Human Untagged Clone

CAT#: SC108847

MAOB (untagged)-Human monoamine oxidase B (MAOB), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Monoamine Oxidase B
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_000898, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGCAACAAATGCGACGTGGTCGTGGTGGGGGGCGGCATCTCAGGTATGGCAGCAGCCAAACTTCTGC
  ATGACTCTGGACTGAATGTGGTTGTTCTGGAAGCCCGGGACCGTGTGGGAGGCAGGACTTACACTCTTAG
  GAACCAAAAGGTTAAATATGTGGACCTTGGAGGATCCTATGTTGGACCAACCCAGAATCGTATCTTGAGA
  TTAGCCAAGGAGCTAGGATTGGAGACCTACAAAGTGAATGAGGTTGAGCGTCTGATCCACCATGTAAAGG
  GCAAATCATACCCCTTCAGGGGGCCATTCCCACCTGTATGGAATCCAATTACCTACTTAGATCATAACAA
  CTTTTGGAGGACAATGGATGACATGGGGCGAGAGATTCCGAGTGATGCCCCATGGAAGGCTCCCCTTGCA
  GAAGAGTGGGACAACATGACAATGAAGGAGCTACTGGACAAGCTCTGCTGGACTGAATCTGCAAAGCAGC
  TTGCCACTCTCTTTGTGAACCTGTGTGTCACTGCAGAGACCCATGAGGTCTCTGCTCTCTGGTTCCTGTG
  GTATGTGAAGCAGTGTGGAGGCACAACAAGAATCATCTCGACAACAAATGGAGGACAGGAGAGGAAATTT
  GTGGGCGGATCTGGTCAAGTGAGTGAGCGGATAATGGACCTCCTTGGAGACCGAGTGAAGCTGGAGAGGC
  CTGTGATCTACATTGACCAGACAAGAGAAAATGTCCTTGTGGAGACCCTAAACCATGAGATGTATGAGGC
  TAAATATGTGATTAGTGCTATTCCTCCTACTCTGGGCATGAAGATTCACTTCAATCCCCCTCTGCCAATG
  ATGAGAAACCAGATGATCACTCGTGTGCCTTTGGGTTCAGTCATCAAGTGTATAGTTTATTATAAAGAGC
  CTTTCTGGAGGAAAAAGGATTACTGTGGAACCATGATTATTGATGGAGAAGAAGCTCCAGTTGCCTACAC
  GTTGGATGATACCAAACCTGAAGGCAACTATGCTGCCATAATGGGATTTATCCTGGCCCACAAAGCCAGA
  AAACTGGCACGTCTTACCAAAGAGGAAAGGTTGAAGAAACTTTGTGAACTCTATGCCAAGGTTCTGGGTT
  CCCTAGAAGCTCTGGAGCCAGTGCATTATGAAGAAAAGAACTGGTGTGAGGAGCAGTACTCTGGGGGCTG
  CTACACAACTTATTTCCCCCCTGGGATCCTGACTCAATATGGAAGGGTTCTACGCCAGCCAGTGGACAGG
  ATTTACTTTGCAGGCACCGAGACTGCCACACACTGGAGCGGCTACATGGAGGGGGCTGTAGAGGCCGGGG
  AGAGAGCAGCCCGAGAGATCCTGCATGCCATGGGGAAGATTCCAGAGGATGAAATCTGGCAGTCAGAACC
  AGAGTCTGTGGATGTCCCTGCACAGCCCATCACCACCACCTTTTTGGAGAGACATTTGCCCTCCGTGCCA
  GGCCTGCTCAGGCTGATTGGATTGACCACCATCTTTTCAGCAACGGCTCTTGGCTTCCTGGCCCACAAAA
  GGGGGCTACTTGTGAGAGTCTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000898 unedited
  NCCGTCANAATTTGTATACGACTCATATAGGCGGCCGCGNATTCGGCACGAGGGCCCANA
  AAACGGAGCAGCGGGCACCAGGGAGGCCTGGAACGGGGCGAGCGCCATGAGCAACAAATG
  CGACGTGGTCGTGGTGGGGGGCGGCATCTCANGTATGGCAGCAGCCAAACTTCTGCATGA
  CTCTTGACTGAATGTGGTTGTTCTGGAAGCCCGGGACCGTGTGGGAGGCAGGACTTACAC
  TCTTAGGAACCAAAAGGTTAAATATGTGGACCTTGGAGGATCCTATGTTGGACCAACCCA
  GAATCGTATCTTGAGATTAGCCAAGGAGCTAGGATTGGAGACCTACAAAGTGAATGAGGT
  TGAGCGTCTGATCCACCATGTAAAGGGCAAATCATACCCCTTCAGGGGGCCATTCCCACC
  TGTATGGAATCCAATTACCTACTTAGATCATAACAACTTTTGGAGGACAATGGATGACAT
  GGGGCGAGAGATTCCGAGTGATGCCCATGGGAAGGCTCCCCTTGCAGAAAAGTGGGACAA
  CATGACAATGAAGGAGCTACTGGACAAGCTCTGCTGGACTGAATCTGCAAAGCAGCTTGC
  CACTCTTTTTGTGAACCTGGTGTGTCACTGCAGAGACCCAATTGAGGTCTCTGCTCTCTG
  GTTCCTGTGGGTATGGGAAAGCAATGGTTGGAGGCACAACAAGAATCATCTCGACACAAA
  TGGAGGACAGGAGAGGAAATTTGTGGGCGGGATCTGGTCAAGTGAGTGAGCGGATAATGG
  ACCTCCTTGGAGACCGAGTGAGCTGGGAGAGCCCTGTGATCTACATTGACCAGACAGAGA
  AAATGGTCCTTGTGGAGACCCTAACCATGAGAGGNATGAGGCTAAAATGGGGAATTAGGG
  CTATTCCTCCTACTCTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000898 unedited
  CGCGGCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTATGGGC
  AATCAACTTTTATTTTTAATTACCCAAGTGTGTACTGGCCTTTGTATGAAGATACAATGG
  AGGATACAAAAGGAAGAAGAGATAAAATTTCTACCATCAAAAAAGTTAAAATCAGCTGGA
  GACACACCGCACAAAACAGTAAGACTTAAGGCTATATACTGAGTAGCATTTGAGAAGTGT
  AAGACAACTTAGCACAGAGTAAACCCACACAACGGGACACCATCGGTAACTATGACAGGG
  AGTGAAGGAGGATAATTGGGGAAAACATCCAAAGAGGGGGGAAAAGCGTTGGATTTGTGT
  TCTAGTCCCCCAGATACCAGTGGCTTATTGGGGCTCTTAAGTAATTAAGTTCCACCTCTG
  TGGGCTTCAGTTTGCTCAACTCTAAAACAGAAGGGGAGGACTAAATGGGCTTTACTGTCT
  TTCAGCTGTAACAATACAGTATTCTAAGGACGAATGCAAAGAACTAGGGAAGGTGAGGCT
  ATTACAGGTAAGAGGAAGAACAAGCACAAAGCCCTAATGGTAGGAAAAAATTCATTCCTT
  GTGCATGGGCAAGGTGTGTTGTGGGGCAGCAAGAACCTTAAACAAGCCAATTTAACTATT
  CTAAAGATTTTGAGGGCAATAAACTTGGAAACTGGTGAAACAGAACGCTAAGCCAGGTAA
  GGGACACTAAGCAGGGGCCACAACGGAGAAAGAATACCATGTATTTTACAGTCAGAGTTG
  GATTTATNTTNATGCNTCCCGNCTNACTCACACTATTTGNCTCATGGAACTTACTGCNAC
  TCTTTCCCAACTCTATCCCAATACAGTAGAGAGATGTGATACAGACACCTCTCTCTTAAC
  TCTACAGTACCCCTTTTGGGGGCAGAAGCAAGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000898
• Insert Size: 2580 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000898.3, NP_000889.3
• RefSeq Size: 2566 bp
• RefSeq ORF: 1563 bp
• Locus ID: 4129
• UniProt ID: P27338
• Cytogenetics: Xp11.3
• Domains: Amino_oxidase
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Arginine and proline metabolism, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Tryptophan metabolism, Tyrosine metabolism
• Gene Summary: The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008]