Nectin 3 (NECTIN3) (BC017572) Human Untagged Clone

CAT#: SC106234

PVRL3 (untagged)-Homo sapiens, nectin 3, clone MGC:24399 IMAGE:4066485, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Nectin 3
• Synonyms: CD113; CDw113; DKFZp566B0846; FLJ90624; nectin-3; nectin 3; poliovirus receptor-related 3; PPR3; PRR3; PVRR3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC017572 edited
  GAATTCGGCACCAGAGTACTTGTAAGTGTTTTGGCTGGAATATTCTGCTATAGGAGAAGA
  CGGACGTTTCGTGGAGACTACTTTGCCAAGAACTACATTCCACCATCAGATATGCAAAAA
  GAATCACAAATAGATGTTCTTCAACAAGATGAGCTTGATTCTTACCCAGACAGTGTAAAA
  AAAGAAAACAAAAATCCAGTGAACAATCTAATACGTAAAGACTATTTAGAAGAGCCTGAA
  AAAACTCAGTGGAACAATGTAGAAAATCTCAATAGGTTTGAAAGACCAATGGATTATTAT
  GAAGATCTAAAAATGGGAATGAAGTTTGTCAGTGATGAACATTATGATGAAAACGAAGAT
  GACTTAGTTTCACATGTAGATGGTTCCGTAATTTCCAGGAGGGAGTGGTATGTTTAGCAA
  CCACTGAATGTGACTTAACTATGTACAATGTTCATTCACACTAGTTGATCATTTTCAGAT
  TGTTCATACTTTTTCTTGAGGAAGAATAAGCTTTTTCAAGTTGATTTTCAAGCTTACTTT
  TTATATTCTAATCTGACAAATGAAAATGTAAAATCTGAGTTCAGTGTATCTAAGCTGCTT
  TACAATTTTTTTTCAATGCTGTACTACTGTCTCAAGATTTAAATTTTAATGCAGAGTACT
  TTATTGGTGTGAGGCACACAGGTAAGAAGAAATGTCAACATTAAATGTATGACTTACTTG
  GTACAAAAATTTTTTAAAAAGGGAACTACCTTGACATTGTGTATTAAATGTTTACCTAAG
  ACTATAATCTCAAGTATGATGTTTGTTTAACATATACCTCTCAAAATTTATCACCACTCA
  ATGACACTGCATCAAAATTGACTATAAAACTAATTCAAGAAATATTTATATATATTTTTT
  AATATACAAAAAATATTTAGCCTGATGGAATGGCTTTCCTTTTCAAACATTATTTTCTAA
  GTTTCTATACAAATGAAATCTTTACCTCTGCATATTAATGAGCCTTGCCATAATTACTGT
  AGAGTGGCTTTTCAAAGATATTTTGTTGCACTAAAACTGTGGTAGTAAACTCAGTGAACA
  TGATGTGTGGAAGAGCATAATTAGCTGGTCAATATTTTTGTCCAAAATACCTGCAAGAGT
  AATAAAATACATACCTTTCAAACATGATAATTATTAGTTTTTTTTTTTCCTTTCTGGAAC
  ATGGATTTTGGTACATTAGCAGTAGCCTTATTTTAATGCTTTATGTCCTAAACATACTAA
  TAGAAATGAAAAGACGCAGAGAGAGCATTTCGGAATACTGAAGTACTAGTTTTAGAAATG
  AGACTTTCAGCCAACAATCTATAXXXXXXXXXXXXXXXXXXXXXXXXXXXXACCAGCCCT
  TTCTCAATATTCATCAAATCTAAAACATTTAGGGGGCAAAATTCTAACATGTTCATGGTA
  TCTTGCAAATAGTGAAAGCTTTATTCTGAAGGATTATAAACTAGTTTTCTTCATTTTAAC
  TAGCACTATTTTGTGGAAATTAGAAACCTCTTTTATTTCTCTTCCCAAAAGTAATACTTA
  TTATAAGGCTGTAGTATCAGGTTAAGGATACAGATAAATAAAGTTCACTTATATCTTCTT
  ACAAATGTCTGGGTTTTAATATGGTTAATCACTTATATACAAATATTACAACTTTTTAGT
  GCAAGTTTTTGGAAGAAAACTTTTTGATAAAACACTGTGATTGATGTGACTTTATTTTTA
  ATTTAAACGATGAGGTGGCCAGAAGAAAGATGGGTCTAAAATTTCTCCCCATGAAAGATG
  TAAAACTATGGCTTTTTTTAAAATCAAAATTTCATCTTTTAAAATAATGGTTTGAAATAC
  TGTATGGATCTGAACAGAATAATCACATTTAGGATTCTATATAAATCTCAACTGGAGTAT
  AATCTGAAGGAAATTAGCAGTGTATTTTAAGAAATATATTTCAAAAATATAAATACTGAT
  TATGAACTTCCTTTTACATTGTGGTTATTTGTGCGATTAGGTTTTTTTGTTTGTTTCTTT
  TGTGTTTGTTTGGCGGGAGAGGGTGACCTGGAAAGCCACAAGTGAGTATTTGACATATTC
  TGTATCCTTAATCCAATCATTTGGCAAACTAAAAGGTTTCTGTGTTGTAAGAATCTGATA
  CTAGTGCTTAAGACTTTGGGAAGCATTGCACTGTTGTTTATTAGAACTTTATGTATATTT
  ACTGTACATAGAGACTTGTTTGAAAACATGAATAGTCATTAAATAAAGACATTGTTAAAT
  TAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC017572 unedited
  NNGGAGTTAGGATTTGTAAACGACTCCTATAGGGCGGCCGCGAATTCGCACCAGNATACT
  TGTAAGTGTTTTGGCTGGAATATTCTGCTATAGGAGAAGACGGACGTTTCGTGGAGACTA
  CTTTGCCAAGAACTACATTCCACCATCAGATATGCAAAAAGAATCACAAATAGATGTTCT
  TCAACAAGATGAGCTTGATTCTTACCCAGACAGTGTAAAAAAAGAAAACAAAAATCCAGT
  GAACAATCTAATACGTAAAGACTATTTAGAAGAGCCTGAAAAAACTCAGTGGAACAATGT
  AGAAAATCTCAATAGGTTTGAAAGACCAATGGATTATTATGAAGATCTAAAAATGGGAAT
  GAAGTTTGTCAGTGATGAACATTATGATGAAAACGAAGATGACTTAGTTTCACATGTAGA
  TGGTTCCGTAATTTCCAGGAGGGAGTGGTATGTTTAGCAACCACTGAATGTGACTTAACT
  ATGTACAATGTTCATTCACACTAGTTGATCATTTTCAGATTGTTCATACTTTTTCTTGAG
  GAAGAATAAGCTTTTTCAAGTTGATTTTCAAGCTTACTTTTTATATTCTAATCTGACAAA
  TGAAAATGTAAAATCTGAGTTCAGTGTATCTAAGCTGCTTTACAATTTTTTTTCAATGCT
  GTACTACTGTCTCAAGATTTAAATTTTAATGCAGAGTACTTTATTGGGTGTGAGGCACAC
  AGGTNAGAAGAAATGTCAACATTAAATGTATGACTTACTTGGTACAAAAATTTTTTAAAA
  AGGGAACTACCTTGACATTGTGTATTAAATGTTTACCTNNAGACTATATCTCAAGTATGA
  TGGTTTGTTTAACATATACCTCTCAAAAATTATCACCACTTCATGACACTGCATCANAAT
  TGACTATTAACTAA
  
• Restriction Sites: NotI-NotI
• ACCN: BC017572
• Insert Size: 2750 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC017572.1, AAH17572.1
• RefSeq Size: 1276 bp
• RefSeq ORF: 306 bp
• Locus ID: 25945
• Cytogenetics: 3q13.13
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Adherens junction, Cell adhesion molecules (CAMs)
• Gene Summary: This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]