Prolactin Receptor (PRLR) (AF493068) Human Untagged Clone

CAT#: SC104829

(untagged)-Human delta 4-delta 7/11 truncated prolactin receptor mRNA, complete cds, alternatively spliced

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PRLR
• Synonyms: HPRL; hPRLrI; MFAB
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for AF493068, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCATGAATGTCCAGACTACATAACCGGTGGCCCCAACTCCTGCCACTTTGGCAAGCAGTACACCTCCA
  TGTGGAGGACATACATCATGATGGTCAATGCCACTAACCAGATGGGAAGCAGTTTCTCGGATGAACTTTA
  TGTGGACGTGACTTACATAGTTCAGCCAGACCCTCCTTTGGAGCTGGCTGTGGAAGTAAAACAGCCAGAA
  GACAGAAAACCCTACCTGTGGATTAAATGGTCTCCACCTACCCTGATTGACTTAAAAACTGGTTGGTTCA
  CGCTCCTGTATGAAATTCGATTAAAACCCGAGAAAGCAGCTGAGTGGGAGATCCATTTTGCTGGGCAGCA
  AACAGAGTTTAAGATTCTCAGCCTACATCCAGGACAGAAATACCTTGTCCAGGTTCGCTGCAAACCAGAC
  CATGGATACTGGAGTGCATGGAGTCCAGCGACCTTCATTCAGATACCTAGTGGTGACCCCTTGATGTTGG
  GTGCCTCTCATTACAAAAATCTCAAATCTTACAGACCAAGAAAAATCTCAAGTCAAGGAAGACTTGCGGT
  GTTCACAAAGGCAACATTGACCACAGTCCAGTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for AF493068 unedited
  NGGTAACCGTTCATAATTTGTCATACGACTCACTATAGGGCGGCCGCGAATTCGCACCAG
  GGGGACCGGGGAGCGGAGGCTGAAATCCCCANACGCCGGTTTTCTGGGCTGGGCTTTCTG
  CCTTACTCACTCCTTCTCCCTCTTTCTGGATTTTACCGACCGTTCGCGAAACAGCTTTCC
  ACACAATGGAGCTTCATGTCCTCGTGCAGGAAGTACTCATCGACTGATGTGGCAGACTTT
  GCTCCCTGGCAAAACTAAAGAACTCTCCTATTCATGGAGGCGAACACTGAGGATGCTTTC
  CACATGAACCCTGAAGTGAACTTCTGATACATTTCCTGCAGCAAGAGAAGGCAGCCAACA
  TGAAGGAAAATGTGGCATCTGCAACCGTTTTCACTCTGCTACTTTTTCTCAACACCTGCC
  TTCTGAATGGACAGTTACCTCCTGGAAAACCTGAGATCTTTAAATGTCGTTCTCCCAATA
  AGGAAACATTCACCTGCTGGTGGAGGCCTGGGACAGATGGAGGACTTCCTACCAATTATT
  CACTGACTTACCACAGGGAAGGAGAGACACTCATGCATGAATGTCCAGACTACATAACCG
  GTGGCCCCAACTCCTGCCACTTTGGCAAGCAGTACACCTCCATGTGGAGGACATACATCA
  TGATGGTCAATGCCACTAACCAGATGGGAAGCAGTTTCTCGGATGAACTTTATGNTGGAC
  GTGACTTACATAGTTCAGCCAGACCCTCCTTTGGAGCTGGCTGTGGAAATAAAACAGCCA
  GAAGACAGGAAACCCTACCTGTGGATTAAATGGTCTCCACCTACCCTGATTGACTTAAAA
  ACTGGTTGGGTCACGCTCCTGTATGAAATTCGATTTAAAACCGGAGAAAGCGCT
  
• Restriction Sites: NotI-NotI
• ACCN: AF493068
• Insert Size: 2500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: AF493068.1, AAM11660.1
• RefSeq Size: 1206 bp
• RefSeq ORF: 1206 bp
• Locus ID: 5618
• Cytogenetics: 5p13.2
• Domains: FN3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]