MRP5 (ABCC5) (AK090667) Human Untagged Clone

CAT#: SC101361

(untagged)-Human cDNA FLJ33348 fis, clone BRACE2003892

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MRP5
• Synonyms: ABC33; EST277145; MOAT-C; MOATC; MRP5; pABC11; SMRP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for AK090667, the custom clone sequence may differ by one or more nucleotides
  
  
  CATTCCTCTGGGTAGCACCATATGCAGGCTTTGCGAATAAAGTGATCATGGGCTTTCTTGATTCCATTTG
  GCCAATGCAAGAACTTCATTGGCTCCCCTCTAAAAAAAATTCCATGGATTGCTGGGATTTTTATTTTTTA
  TTTTTTGAAAAAAATGGTACCTATCCGTATTCAGCTTGGTGGCTTCACAGTCCCTCCCCTGAACATCCGT
  ATATTCCTTATTCTCTCATTTATGGTGCAGAACACTGGGGTACTAACCTCTAGGAAACTGTTCTAGCTGC
  CAGGGAAAGCTAAGAGCCCTCCTTTAACAGGAAAGCAGCAGCATGCTTTTTCTTCTCTCTGCCGTTTCAG
  GGAAGAGCACCTTAAGGCCAGTGTTATTTCATGGGATTCTGTCCTAGAGCTGAGAAAGTAATGGACTCAT
  CCATAATCTCTTTTATAGATTTGAAAGTGTAAACAATACACACTTCCTTTTTTGGAACTCCAATTCTAAT
  ATGTTTCTTTTTCATTGGAAATTGAAAAACCAGGCTGGTTTTGAGATTAGTACTAGCAGTGAGTAAACCT
  CCTGTCTGTGGACTTAAATCCTTTTGAGGAACATTTCGTTTTAGATTTTTACAAGTTTTCTAATCTGGCA
  CGACTTTCAAACTAGCTTAATCTGTTCTTACAGAAACCTGTGTAAGGACAGACTGCCCACATACGGGCTC
  CCCAAACAAAACGGCATTTTTATTTCTTGTCCCTGCTCGGGTTTCACCGAACCTTGGTAGCCATAATCAG
  AACAAATGAAACACAGTCAAGTTGTTGTGTTCTGTTTGTTTTTACCTGCCAGCCAGCTGATGCTGACATT
  TATACACCAAGATGATCCAAGGTTTTGGTGACGCCGGTGGGGACTGCCGCTATATGTGCAGGGTGCCCGG
  GGGTCATAGTAATGTTAATGGAGTACCAGAATCTCTAACAGTGTGGTCCTGTGTAGCCACATTGCTACAC
  TTACAGAGATGCTTTGGGGCCTTTTTGGATTAAGACAGTTCTAAAAGACCAGGCCTCACCTATGATCTGT
  GTATAAAGAATTAGCATCGCACTGTAGATCTGCAAGAGAAGGCCGCCTCCTGCAGTGCTCTCTCTTGGTG
  AATGCTAACTCTGCTCGAGGGCCTTTTGGGGAAAGGACAGTGCAAAACCCTTAGAGAGGTAAGTTTCCCA
  CCCTTCCAACCTCTCTCCACCTGCAGCTTGCTTGGTGCTGTCAGGATCTGGATTTGGGGGGAGTCTCTCT
  GTAGTGGAACCAGTGACAGAAGCTGTTCTTTAGAATTTTCAGGATGGCTGTATTCTGCGGTCAGAATGAG
  AGAGTCAAGCTGGGCAGAATCTCTCGCCAAGAGTTCAGGTAAGGTAATGTTTATTCACTGGGAATGCTTT
  CCACAGCCAGACAGCTATGCTAACAGTCTCAAGTTTTCTTCCAGTTTGTTTAGATTTAAATGATACATTT
  GTAACTTTTTAAAAACTAAATTTTGGTTGGATTTTTCATGAAAACCTCTTTTTTCTTTATCCCCTAAAAA
  ATGGTTTGAAATGTCATTGTTATTTAAAAACCCGATGTGTTGGAACTTCTTTAATCTGCTGTTTCCTCTT
  TTTCCCCCCCTTTGAAAGTTTCGCATAGTGTAAACATTCACTATGTCTTTTACCTTCCCTGCTCCTCCCA
  TCTGGGAGGCGCTGATGCTATTACCCAGTGCTGAAAAATGGCACTCTAAAGGTATGGGAAGGAAGGAGCC
  CAAGGCAACCACCTGCTGTCCTTTCAGCCTTCCTTTGGAGACTGCTCCATCAGTGCCGAGGTGTGTGGGA
  ACAGGCTTCACTGCACCGCCATCTTACTGAGTTGCTTCACGTGAGGAAAAGGGGGCTTTGGCCCTGTGAC
  TCAGTTCCACATTTTGGATTGCATACTGGAAAAGAAGCCAATCTTCTTGCTAGTAAACCAGCAACCCGGC
  TGTATACAGTGGTGACCCAAGCAATGGATATAAACCTAAAAATCTGAGGGAGGGGAGAGGTGGAATACAG
  TAGTTCTTGGAATCTGAAGTCTCCTATTTGATCAGGTTATTTCCTGGGACTTGGCAAAAATCTGATTGGT
  GGGGATCTCCTAGGACCTAGTGGACATCTGGTATTAATTTAATCTCAGGAAAAACAAGAAATTAACCCAG
  AGAGAGTCTGGGTTCTGGAATTCAGCGTAGCTACCTCCAGACCGTGGTGTCTGGCCTCCATTTTTGTCTG
  TCATTCAGCTCTGACTTACAGCTGCAATCACCTTTGCTATAAGGCACCTGGGTAGAAGGGTGGATGGGCT
  TCACATCAATTTTTTTCTTCCTTTAGGGTGGGGGATTGGTTTGGCTTTCTTTTGTTGTGGCTTTTTGTTT
  TATTTTTGTCAAGATTGATTTTTAGATGCAAGGACTTGAAAAGACCCAGAAGGATGCCACCAGTTTTTCC
  TTGAGGCCTAGGATTTTTTATTCTGTCCCGAGCAGAGGTAATTCCTCACAACTTAGTGCACCAGTAGCAC
  CAGCCGTTTTGAGCAGAGTACCTCTTTGGGGAGCTTTTCGTTTTGTTTTGTTTTTAATTCTCTTTCCTTA
  GCAGCAAGGTCTTTTTTCCTAGAGAATCTACTCCGTTGCAGAATCATTGCAACCTCAGGAGCCCTCACTG
  ATTGAGTGCTGTCAGCCTGATATACTACTTTGGACTCTGGAAACAGATATGGGTTCTATTCTCTATTTCT
  ACTGTGTGTCGTTAAACAACCGTCGGAGACCAGATGACCTGTTAGATGGCTAGTCCTGTATAACTCGACT
  CTGTATGTTTCAATGTATGTTACTGCAATGCTTCACCTGCTGTACAGTGTTTGTGAGATGCTCTTTGAAG
  ATGGTACTTTTATATTTTTTCATTTTCAATAAAAGTACATTCCTTCCC
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for AK090667 unedited
  NGGTCAAATATTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGATGAAACA
  CAGTCAAGTTGTTGTGTTCTGTTTGTTTTTACCTGCCAGCCAGCTGATGCTGACATTTAT
  ACACCAAGATGATCCAAGGTTTTGGTGACGCCGGTGGGGACTGCCGCTATATGTGCAGGG
  TGCCCGGGGGTCATAGTAATGTTAATGGAGTACCAGAATCTCTAACAGTGTGGTCCTGTG
  TAGCCACATTGCTACACTTACAGAGATGCTTTGGGGCCTTTTTGGATTAAGACAGTTCTA
  AAAGACCAGGCCTCACCTATGATCTGTGTATAAAGAATTAGCATCGCACTGTAGATCTGC
  AAGAGAAGGCCGCCTCCTGCAGTGCTCTCTCTTGGTGAATGCTAACTCTGCTCGAGGGCC
  TTTTGGGGAAAGGACAGTGTAAAACCCTTAGAGAGGTAAGTTTCCCACCCTTCCAACCTC
  TCTCCACCTGCAGCTTGCTTGGTGCTGTCAGGATCTGGATTTGGGGGGGAGTCTCTCTGT
  AGTGGAACCAGTGAAGAAAGCTGTTCTTTAGAATTTTCAGGATGGCTGTATNCTGCGGTC
  AGAATGAGAGAGTCAAGCTGGGCAGAATCTCTGCCAAGAGTTCAAGTAAGGTAATGTTTA
  TTCACTGNGAATGCTTTCCACAGCCAGACAGCTATGCTAACAGTCTCAAGTTTTCTTCNC
  AGTTTGTTTAGATTTAAATGATACATTTGTAACTTTTTAAAATAAATTTTGNTTTGGATT
  TTTCATGAAAACCTCTTTTTTCTTTATCCCTANAAAATGGTTNGAATGTCATTGNTATTT
  AAAAACCGATGTGTTGGAAACTCTTAATCTGCTGTTNCCTCTTTTCCCCCTTTTGAAAGT
  TCGCATATGGTAACATCACTATGNCTTTTACTTCCTGCTCTCATATNNGNAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for AK090667 unedited
  NGGGGGAATACTGTGNNACGCGGNCCGCTTNCNANGATCGAGTTTTTTTTTTTTTTTTTT
  GGGGAAGGAATGTACTTTTATTGAAAATGAAAAAAATAAAAGTACCATCTTCAAAGAGCA
  TCTCACAAACACTGTACAGCAGGTGAAGCATTGCAGTAACATACATTTGAAACATACAGA
  GGTCGAGTTATACAGGACTAGCCATCTAACAGGTCATCTGGTCTCCGACGGTTGTTTAAC
  GACACACAGTAGAAATAGAGAATAGAACCCATATCTGTTTCCAGAGTCCAAAGTAGTATA
  TCAGGCTGACAGCACTCAATCAGTGAGGGCTCCTGAGGTTGCAATGATTCTGCAACGGAG
  TAGATTCTCTAGGAAAAAAGACCTTGCTGCTAAGGAAAGAGAATTAAAAACAAAACAAAA
  CGAAAAGCTCCCCAAAGAGGTACTCTGCTCAAAATGGCTGGTGCTACTGGTGCACTAAGT
  TGTGAGGAATTACCTCTGCTCGGGACAGAATAAAAAATCCTAGGCCTCAAGGAAAAACTG
  GTGGCATCCTTCTGGGTCTTTTCAAGTCCTTGCATCTAAAAATCAATCTTGACAAAAATA
  AAACAAAAAACCACAACAAAAGAAAGCCAAACCAATCCCCCACCCTAAAGGAAGAAAAAA
  ATTGATGTGAAGCCCATCCACCCTTCTACCCANGTGCCTTATAGCAAAGGTGACTGCAGC
  TGTTAGTCAGAGCTGAATGACAGACAAAAATGGAGGCCAGACACCACGGTCTGGAGGTAG
  CTACGCCTGATTCCAGAACCCAGACTCTCTCTGGGGGTAATTTTCTGGTTTTCCCTGAGA
  TTAATTAATTACAGATGTCCACTAAGTCCTAGGAGATCCCACCCATCAGATTTTTGCCCA
  GTCCCG
  
• Restriction Sites: NotI-NotI
• ACCN: AK090667
• Insert Size: 2500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: AK090667.1
• RefSeq Size: 2918 bp
• RefSeq ORF: 2918 bp
• Locus ID: 10057
• Cytogenetics: 3q27.1
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ABC transporters
• Gene Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]